直肠癌患者腹腔镜手术中淋巴结检出数量的相关因素研究  

Study on the related factors of lymph node detection number in rectal cancer patients underwent laparoscopic surgery

作　　者：何华[1] 谢嵘[1] 党胜春[1] 黄润生[1] 张清[1] 瞿建国[1] 陈吉祥[1] 崔磊[1] Hua He;Rong Xie;Sheng-chun Dang;Run-sheng Huang;Qing Zhang;Jian-guo Qu;Ji-xiang Chen;Lei Cui(Department of Gastrointestinal Surgery, the Affiliated Hospital of Jiangsu University,Zhenjiang, Jiangsu 212001, China)

机构地区：[1]江苏大学附属医院胃肠外科,江苏镇江212001

出　　处：《中国内镜杂志》2017年第12期9-13,共5页China Journal of Endoscopy

基　　金：镇江市科技计划(社会发展)项目(No:SH2015066)

摘　　要：目的探讨直肠癌腹腔镜手术淋巴结检出数量的相关因素。方法选取2014年1月-2017年1月于该院行腹腔镜下微创手术治疗的98例直肠癌患者为研究对象。统计患者一般资料[性别、年龄、体质指数(BMI)]、术前影像学检查结果、临床病理资料(肿瘤大小、大体类型、TNM分期、远处转移、组织分化程度和浸润深度等)、手术情况(术者、手术时间)和术前放化疗情况。结果年龄、BMI、肿瘤大小、标本长度、浸润深度、术者情况、术前放化疗与直肠癌微创手术患者淋巴结检出数量有关(P<0.05),而性别、TNM分期、大体类型、组织分化程度、手术时间与直肠癌微创手术患者淋巴结检出数量无关(P>0.05)。多元线性回归分析结果表明,BMI、肿瘤大小、标本长度、浸润深度、术者和术前放化疗是直肠癌微创手术患者淋巴结检出数量的独立影响因素(P<0.05)。结论患者因素、肿瘤状况、手术因素均及治疗情况与直肠癌微创手术淋巴结检出数量有关。Objective To investigate the related factors of lymph node detection number in rectal cancer patients underwent laparoscopic surgery.Methods98patients with rectal cancer who underwent laparoscopic surgery were selected from January2014to January2010.All the patients general information[gender,age,body mass index(BMI)],preoperative imaging findings and pathological data(tumor size,gross type,TNM stage,distant metastasis,histological differentiation and depth of invasion,et al),surgery related data(experience of surgeon,operation time)and preoperative radiotherapy and chemotherapy were collected.Results The age,BMI,tumor size,length of specimen,invasive depth,surgeon and preoperative radiotherapy and chemotherapy was correlated with the number of lymph nodes in patients with laparoscopic surgery(P<0.05),but gender,TNM staging,general type,histological differentiation,operation time were not associated with the number of lymph nodes detected in minimally invasive surgery for rectal cancer(P>0.05).Multiple linear regression analysis showed that BMI,tumor size,length of specimen,invasive depth,surgeon and preoperative radiotherapy and chemotherapy were the independent influencing factors of lymph node detection in patients with minimally invasive rectal cancer(P<0.05).Conclusion The factors of patients,tumor status,surgical factors and preoperative chemoradiotherapy are related to the number of lymph nodes in patients with rectal cancer.

关 键 词：直肠癌 腹腔镜手术 淋巴结 数量 因素 

分 类 号：R735.37[医药卫生—肿瘤]