普芦卡必利用于老年结肠镜前肠道准备的效果及干预时长观察  

Observation of the effect and the length of intervention on the bowel preparation before colonoscopy in the elderly

作　　者：温艳清[1] 马海英[1] 张旭[1] Wen Yanqing;Ma Haiying;Zhang Xu(Faculty of Pharmaceutical Sciences, Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China)

机构地区：[1]中国医科大学附属第四医院药学部,沈阳110032

出　　处：《中华结直肠疾病电子杂志》2017年第6期494-497,共4页Chinese Journal of Colorectal Diseases(Electronic Edition)

摘　　要：目的研究普芦卡必利用于老年结肠镜前肠道准备的效果及干预时长。方法选取中国医科大学附属第四医院90例老年结肠镜前肠道准备患者为研究对象,随机分为三组,A组单纯给予聚乙二醇电解质散溶液,结肠镜检查前4 h给予,B、C组另加用普芦卡必利,分别在结肠镜检前1 d、3 d使用,比较三组清洁效果、肠道内气泡情况及息肉检出率。结果 B、C组横——降结肠、直肠——乙状结肠、升结肠——回盲部清洁评分均显著高于A组(P<0.05),B、C两组在上述部位清洁评分比较差异无统计学意义(P>0.05);B、C气泡显著少于A组(Χ~2值分别为5.455,4.022,P均<0.05),B、C两组组间比较差异无统计学意义(P>0.05);三组>10 mm和三组≤10 mm息肉检出率比较差异无统计学意义(Χ~2值分别为0.207,0.274,P均>0.05)。结论普芦卡必利联合聚乙二醇电解质散溶液用于结肠镜前肠道准备效果显著,可改善清肠效果,降低肠道内气泡情况,可作为老年结肠镜前检查的有效方式。Objective To study the effect and the length of intervention on the bowel preparation before colonoscopy in the elderly.Methods We selected90elderly patients with intestinal tract preparation before colonoscopy,and divided into three groups,group A was treated with polyethylene glycol electrolyte solution only4h before colonoscopy,Group B and group C were treated with prucalopride and polyethylene glycol electrolyte solution1d and3d before colonoscopy respectively,the cleaning effect,intestinal bubble status and polyp detection rate were compared between the three groups.Results Descending colon,sigmoid colon,ascending colon and rectum-ileocecus clean scores of B and C groups were significantly higher than that of group A(P<0.05),there was no significant difference between the two groups of B and C(P>0.05).The bubbles of group B and C were significantly less than that of group A(P>0.05),there was no significant difference between the two groups of B and C(P<0.05),in the three group,the polyp detection rate had no significant difference(Χ2=0.207,Χ2=0.274,all P>0.05).Conclusion Prucalopride combined with polyethylene glycol electrolyte solution for the bowel preparation is effective,which can improve the clearing effect,reduction of intestinal air bubbles,can be used as an effective method for colonoscopy examination in elderly patients.

关 键 词：普芦卡必利 肠道准备 老年 结肠镜 

分 类 号：R574.62[医药卫生—消化系统]