推拿手法联合跑台训练对坐骨神经延期缝合大鼠神经再生的效果  

Effect of Tuina Combined with Treadmill Training on Nerve Regeneration after Sciatic Nerve Delayed Suture in Rats

作　　者：陆永嘉[1] 严隽陶[1] 马书杰 陶然 马颖[1] 史智君 孔亚敏 王春红[1] LU Yong-jia;YAN Jun-tao;MA Shu-jie;TAO Ran;MA Ying;SHI Zhi-jun;KONG Ya-min;WANG Chun-hong(Department of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai Univesity of Traditional Chinese Medicine, Shanghai 200437, China;College of Rehabilitation, Shanghai Univesity of Traditional Chinese Medicine, Shanghai 201203, China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院推拿科,上海市200437 [2]上海中医药大学康复医学院,上海市201203

出　　处：《中国康复理论与实践》2017年第11期1273-1277,共5页Chinese Journal of Rehabilitation Theory and Practice

基　　金：国家自然科学基金面上项目(No.30973806;No.81373764);国家自然科学基金青年基金项目(No.81603713)

摘　　要：目的探讨推拿手法联合跑台训练对坐骨神经横断伤延期外膜修复后促进神经再生的效果。方法 60只Sprague-Dawley大鼠随机等分为对照组、模型组和治疗组。后两组建立坐骨神经横断伤延期外膜缝合模型,治疗组给予捏法推拿及跑台训练,每天1次。分别于干预后1个月、2个月各取10只大鼠检测坐骨神经运动神经传导速度(MCV)、再生神经轴突数及施万细胞数,电镜观察超微结构。结果与模型组比较,治疗组MCV在干预后2个月加快(P<0.05),轴突数无显著性差异(P>0.05),施万细胞数增加(P<0.05),电镜下损伤较轻。结论推拿手法联合跑台训练可促进损伤的周围神经再生。Objective To explore the effect of the combination of Tuina and treadmill training on nerve regeneration after sciatic nerve transection.Methods A total of60Sprague-Dawley rats were randomly divided into control group,model group and treatment group equally.The sciatic nerve was transected in the latter two groups and the epineurium suture was delayed four days.Then the treatment group accepted Tuina and treadmill training once a day.The motor conduction velocity(MCV)of sciatic nerve was measured one and two months after intervention in ten rats respectively,while the number of regenerated axons and Schwann cells was counted,and structures of sciatic never were observed under electron microscopy.Results Compared with the model group,the MCV accelerated in the treatment group(P<0.05),the number of axons was not significantly different(P>0.05),and the number of Schwann cells increased two months after modeling(P<0.05),with less injury under electron microscopy.Conclusion Tuina combined with treadmill training can promote the regeneration of the injured peripheral nerve.

关 键 词：坐骨神经 神经再生 推拿 跑台训练 大鼠 

分 类 号：R745[医药卫生—神经病学与精神病学]