3种恶性成分的腮腺区多形性腺瘤癌变1例报告及文献复习  

Carcinoma ex pleomorphic adenoma composed of three malignant components in parotid gland:A case report and literature review

作　　者：孙兰芳[1] 及昕[1] 史册[2] 韩茹钰 张宁[1] 韩明林 李明贺[1] 韩成敏[1] SUN Lanfang;JI Xin;SHI Ce;HAN Ruyu;ZHANG Ning;HAN Minglin;LI Minghe;HAN Chengmin(Department of Oral and Maxillofacial Surgery, Stomatology Hospital,Jilin University, Changchun 130021, China;Department of Pathology, Stomatology Hospital,Jilin University, Changchun 130021, China;Department of Orthodontics, Stomatology Hospital,Jilin University, Changchun 130021, China)

机构地区：[1]吉林大学口腔医院口腔颌面外科,吉林长春130021 [2]吉林大学口腔医院病理科,吉林长春130021 [3]吉林大学口腔医院正畸科,吉林长春130021

出　　处：《吉林大学学报（医学版）》2017年第6期1265-1267,共3页Journal of Jilin University：Medicine Edition

基　　金：吉林省科技厅自然科学基金资助课题(3D515V663431);吉林省卫计委青年科研基金资助课题(3D514CP23431)

摘　　要：目的:探讨1例含有3种恶性成分的腮腺区多形性腺瘤癌变(CXPA)患者的诊断和预后,提高临床医生对该病的认识。方法:患者因左腮腺区肿物30年余伴疼痛1个月入院,经腮腺区彩超检查后行左腮腺区肿物切除术。结果:该患者手术过程顺利,术后病理诊断为CXPA,包含非特异性腺癌、导管癌和肌上皮癌3种恶性成分。结论:同时含有多种恶性成分的CXPA临床罕见,诊断困难,预后差,临床医师应提高对该病的认识。Objective:To investigate the diagnosis and prognosis of one patient with carcinoma ex pleomorphic adenoma(CXPA).composed of three malignant.components in parotid gland,and to raise the clinicians’awareness of the disease.Methods:A patient was presented to hospital because of the mass in left parotid gland region for more than30years and the accompanied pain lasted for one month.After color ultrasonography,the left parotid gland tumor resection was performed.Results:The operation was successful.The postoperative pathological diagnosis results.comfirmed as CXPA,it was.composed of three malignant.components,including non specific adenocarcinoma,ductal carcinoma,and myoepithelial carcinoma.Conclusion:CXPA.composed of three malignant.components at the same time are extremely rare.CXPA is difficult to diagnose and its prognosis is poor.The clinicians are supposed to improve the understanding of CXPA.

关 键 词：多形性腺瘤癌变 多形性腺瘤 非特异性腺癌 导管肿瘤 肌上皮肿瘤 

分 类 号：R782[医药卫生—口腔医学]