中央孔后房型人工晶体植入术矫正屈光不正的疗效  

Effect of posterior chamber phakic intraocular lens with a central hole on refractive errors

作　　者：陈海婷[1] 牛广增[1] 冯雪艳[1] 刘逾[1] 范玉香[1] CHEN Haiting;NIU Guangzeng;FENG Xueyan;LIU Yu;FAN Yuxiang(Department of Ophthalmology, Cangzhou Central Hospital, Cangzhou Hebei 061000, China)

机构地区：[1]河北省沧州市中心医院眼一科,河北沧州061000

出　　处：《Eye Science》2017年第4期206-212,共7页眼科学报（英文版）

摘　　要：目的:观察后房型有晶体眼人工晶体(implantable collamer lens,ICL)V4c植入术后2年的有效性、安全性和稳定性,评估ICL V4c矫正屈光不正的中远期临床疗效。方法:回顾性病例研究。收集在河北省沧州市中心医院眼一科行ICL V4c手术治疗的屈光不正患者,观察并记录术前至术后2年的裸眼视力、最佳矫正视力、屈光状态、对比敏感度、高阶像差、眼压、人工晶体拱高、角膜内皮细胞计数、不良反应、主观视觉质量等临床资料,进行统计学分析。结果:完成随访的96例术眼,术后2年的平均裸眼视力(Log MAR)为0.021±0.065,平均最佳矫正视力(Log MAR)为0.002±0.041,优于术前最佳矫正视力,有效性指数为1.05,安全性指数为1.09,等效球镜数值稳定,对比敏感度提升,高阶像差有所增加,但主观视觉质量良好,眼压基本稳定,内皮细胞丢失率为1.6%,平均拱高为(549.6±50.0)μm,随访期间未发现眼内感染、继发性青光眼、晶状体混浊、黄斑水肿、视网膜脱离等并发症。结论:ICL V4c植入术矫正屈光不正具有良好的中远期临床效果。Objective:To assess the medium-long term efficacy,safety and stability of a newly developed posterior chamber phakic intraocular lens(model V4c Visian Implantable Collamer Lens)to correct refractive errors.Methods:Retrospective case series.This study evaluated eyes that had implantation of ICL V4c to correct ametropia for at least two years.Uncorrected and corrected distance visual acuities,refraction,contrast sensitivity,high-order aberration,quality of life,intraocular pressure,endothelial cell density,pIOL vault,and adverse events were evaluated to assess the efficacy,safety and stability of V4c.Results:The study comprised96eyes of50patients.At2years postoperatively,the mean uncorrected distance visual acuity(UDVA)and corrected distance visual acuity(CDVA)were0.021±0.065logMAR and0.002±0.041logMAR,which were better than preoperative CDVA.The efficacy and safety indices were1.05and1.09,respectively.The spherical equivalent was stable with improved contrast sensitivity and increased high-order aberrations,but the subjective visual quality was well.The IOP remained stable over time.The mean vault was(549.6±50.0)μm and the mean endothelial cell loss was1.6%.No eye developed intraocular infection,secondary glaucoma,lens opacity,macular edema or retinal detachment.Conclusion:The good medium-long term outcomes support the use of ICL V4c for the correction of myopia.

关 键 词：有晶体眼人工晶体植入 眼内镜 屈光不正 

分 类 号：R779.6[医药卫生—眼科]