肝癌患者肝剪切波值与术后并发症的关系  

Relationship between shear wave velocity and postoperative complications in patients with patients with hepatocellular carcinoma

作　　者：刘晓燕[1] 李媛媛[1] 王建华[1] 夏良华[2] LIU Xiaoyan;LI Yuanyuan;WANG Jianhua;XIA Lianghua(Department of Ultrasound,Erdos Central Hospital,Inner Mongolia 017000,China)

机构地区：[1]内蒙古鄂尔多斯市中心医院超声科,017000 [2]同济大学附属上海东方医院超声科

出　　处：《临床超声医学杂志》2017年第12期820-823,共4页Journal of Clinical Ultrasound in Medicine

基　　金：上海市浦东新区卫生局卫生科技项目(PW2012A-24)

摘　　要：目的探讨肝癌患者肝剪切波值(SWV)与术后并发症的关系。方法选取150例行肝癌手术切除的患者作为研究对象,比较不同肝纤维化程度及术后并发症严重程度患者肝SWV,分析SWV与不同肝癌术后并发症分级的关系;绘制ROC曲线分析SWV和肝纤维化分级在预测术后严重并发症上的准确性,并对其进行比较。结果随着不同肝纤维化程度及术后并发症严重程度的增加,SWV呈显著上升趋势,差异均有统计学意义(均P<0.05);且SWV与并发症严重程度呈显著正相关(r=0.701,P=0.000)。肝纤维化分级预测严重并发症的曲线下面积为0.722,最佳截断点为S1,其敏感性为90.00%,特异性为42.31%;SWV预测严重并发症的曲线下面积为0.871,最佳诊断值为1.74 m/s,其敏感性为90.00%,特异性为69.23%。SWV的诊断效能高于肝纤维化分级,但二者差异无统计学意义(Z=1.552,P=0.121)。结论 SWV可用于术前评估患者肝癌术后严重并发症。Objective To explore the relationship between shear wave velocity(SWV)and postoperative complications in patients with hepatocellular carcinoma.Methods One hundred and fifty patients with hepatocellular carcinoma were involved.The differences of SWV between different degree of liver fibrosis and postoperative complications were compared.The relationship between SWV and the grade of postoperative complications of hepatocellular carcinoma was analyzed.ROC curve was drawn to compare the accuracy of the SWV and liver fibrosis grading in predicting surgical complications.Results With the increase of liver fibrosis grade and the severity of complications,the SWV showed a significant upward trend,the differences were statistically significant(both P<0.05).There was a significant positive correlation between SWV and severity of complications(r=0.701,P=0.000).The area under ROC curve of liver fibrosis grading in predicting the severity of complications was0.722,with a cutoff value of S1,a sensitivity of90.00%and a specificity of42.31%,respectively.And the area under ROC curve of SWV was0.871,with a cutoff value of1.74m/s,a sensitivity of90.00%and a specificity of69.23%,respectively.The diagnostic efficiency of SWV was higher than that of liver fibrosis grade,but the difference was not statistically significant(Z=1.552,P=0.121).Conclusion SWV can be used for preoperative evaluation of patients with severe postoperative complications of hepatocellular carcinoma.

关 键 词：声脉冲辐射力成像 剪切波值 肝癌 肝纤维化 并发症 

分 类 号：R735.7[医药卫生—肿瘤] R445.1[医药卫生—临床医学]