结直肠癌患者术前血小板计数水平与肿瘤临床病理分期的关系  

Association of platelet count and clinicopathological characteristics in colorectal cancer

作　　者：张俊 宁忠良 赵旭辉[1] 魏忠[1] 樊平[1] 戴寅[1] 谢钊[1] ZHANG Jun;NING Zhongliang;ZHAO Xuhui(Department of Gastrointestinal Surgery, Anhui Provincial Cancer Hospital(West Branch of Anhui Provincial Hospital), Hefei 230031, China)

机构地区：[1]安徽省肿瘤医院(安徽省立医院西区)胃肠外科,合肥230031

出　　处：《安徽医学》2017年第12期1529-1532,共4页Anhui Medical Journal

摘　　要：目的探讨结直肠癌患者术前血小板计数水平与肿瘤临床病理分期的关系。方法回顾性分析2015年1月至2016年12月安徽省肿瘤医院胃肠外科经组织病理学确诊的420例结直肠癌患者的临床资料,统计不同临床分期结直肠癌患者血小板增多症的发生率。结果结直肠癌血小板增多症发生率与肿瘤分化程度、淋巴转移、性别、年龄、肿瘤部位均无密切关系(P>0.05)。初诊时发现血小板增多症70例(16.67%),术后TNM I期70例,Ⅱ期99例,Ⅲ期217例,Ⅳ期34例,血小板增多症发生率依次为7.14%、14.14%、18.89%和29.41%,差异有统计学意义(P<0.05)。结论结直肠癌患者临床病理分期与血小板增多有密切关系。ObjectiveTo explore the relationship between platelet count and colorectal cancer at the points of clinicatholocal stageand the prognosis.Methods The clinical data of420colorectal cancer patients from January2015to December2016were retrospectively analyzed.The frequency of patients with thrombocytosis in different clinicopathological stages was analyzed.Results Platelet count was associated with histological grade,distant metastasis,type,invasion depth and tumor stage(P<0.05),but not with degree of differentiation,lymph node metastasis,gender,age and tumor location(P>0.05).16.67%patients with colorectal cancer were accompanied with thrombocytosis.The frequency of patients with thrombocytosis in I(70cases),II(99cases),III(217cases),IV stage(34cases)were7.14%,14.14%,18.89%,29.41%,respectively and the difference was statistically significant(P<0.05).Conclusion There is a close relationship between platelet count and colorectal cancer.

关 键 词：结直肠癌 临床病理特征 血小板增多症 

分 类 号：R735.3[医药卫生—肿瘤]