帕金森病患者疼痛的患病率及临床特点  

Prevalence and clinical characteristics of pains in Parkinson disease

作　　者：邓娟[1] 刘俐[1] 黄静[2] 陈德智[2] Deng Juan;Liu Li;Huang Jing;Chen Dezhi(Department of Pain Management,West China Hospital,Sichuan University,Chengdu610041,China;Department of Neurology,West China Hospital,Sichuan University,Chengdu610041,China)

机构地区：[1]四川大学华西医院疼痛病房,四川成都610041 [2]四川大学华西医院神经内科,四川成都610041

出　　处：《现代临床护理》2017年第10期7-11,共5页Modern Clinical Nursing

摘　　要：目的探讨帕金森病(Parkinson disease,PD)患者疼痛的患病率及其临床特点,为更好地制订护理和治疗措施提供依据。方法 2015年11月-2016年11月在本院神经内科进行一项横断面对照研究。选择316例应用简易智能状态量表(mini-mental state examination,MMSE)评分≥24分的人群,其中包括162例PD患者组和154例健康人群对照组。对两组利用第2版简明健康状况量表(medical outcomes study 36-item short-form health survey,SF-36v2)中的"躯体疼痛(bodily pain,BP)"维度的条目7,对受试者是否存在疼痛以及疼痛程度进行评估;并利用一幅包括45个解剖区域的人体插图,让受试者指出疼痛的位置分布。了解两组受试者疼痛患病率、疼痛程度及其分布情况。结果两组疼痛患病率比较,P<0.001,差异有统计学意义,PD患者组疼痛患病率明显高于对照组;两组疼痛程度比较,P<0.001,差异有统计学意义,PD患者组疼痛程度明显重于对照组;PD患者组和对照组最常出现疼痛的部位主要位于下腰部,其他依次位于臀部、小腿、大腿、后颈部、肩部,而且两组不同部位患病率比较,均P<0.05,差异有统计学意义,PD患者组不同部位率明显高于对照组。结论 PD患者较健康人群疼痛患病率高,疼痛程度明显,疼痛部位不尽相同。医护人员应对PD患者组疼痛情况引起重视,依据其疼痛临床特点给予针对性的护理与治疗,以便提高PD患者的生活质量。Objective To study the pain prevalence and clinical characteristics in Parkinson disease(PD)for better understanding its pathophysiology and improving nursing care and treatment.Methods A cross-sectional controlled study was conducted at Department of Neurology,West China Hospital of Sichuan University from November2015to November2016.A total of316subjects with mini-mental state examination scores≥24were enrolled,including162PD patients and154controls.Pain was assessed using the medical outcomes study36-item short-form health survey(SF-36v2)bodily pain scale,and a body illustration including45anatomical areas for subjects to indicate the prevalence,severity and location of pain.Results Pain prevalence and severity in the PD group were significantly higher than those in the control group(P<0.001).Pain distribution was similar between groups,predominantly in the lower back,followed by the gluteal region,lower legs,thighs,posterior neck,and shoulders,but the prevalence of pain location in each between groups was with statistical significance(all P<0.05).Conclusions Pain prevalence in the PD group is significantly higher than that of normal people as well as its severity,but both groups are not similar in pain location.Pain is a significant problem in daily life of PD patients.Recognition of this has the potential to aid the better clinical management of and improved quality of life for PD patients.

关 键 词：帕金森病 疼痛 患病率 

分 类 号：R742.5[医药卫生—神经病学与精神病学]