UPLC–MS–MS法测定塑料包装材料中四溴双酚A  

Determination of tetrabromobisphenol A in plastic packaging materials by UPLC–MS–MS

作　　者：卢任杰 郑增尧 韩飞 邱丰艳[3] 丁力[3] 陈雪梅[3] LU Renjie;ZHENG Zengyao;HAN Fei;QIU Fengyan;DING Li;CHEN Xuemei(Shantou Food Inspection and Test Center 515041,China;Guangdong Shantou Institute of Quality and Metrology Supervision Testing,Shantou 515041,China;College of Life Science,Longyan University,Longyan 364012,China)

机构地区：[1]汕头市食品检验检测中心,广东汕头515041 [2]广东省汕头市质量计量监督检测所,广东汕头515041 [3]龙岩学院生命科学学院,福建龙岩364012

出　　处：《化学分析计量》2018年第2期18-21,共4页Chemical Analysis And Meterage

基　　金：汕头市科技计划项目[汕府科[2015]132号文](102);广东省质监局科研项目(2017PZ12);福建省中青年教师教育科研项目(JAT160496)

摘　　要：建立超高效液相色谱–串联质谱法(UPLC–MS–MS)测定塑料包装材料中四溴双酚A的含量。塑料包装材料样品经研磨粉碎后,采用纯甲醇进行超声萃取,萃取液经氮吹浓缩后用UPLC–MS–MS测定。四溴双酚A的质量浓度在2.5~50 ng/g范围内与色谱峰面积呈良好的线性关系,线性相关系数为0.999 8,检出限为0.6μg/kg,定量限为2.0μg/kg。加标平均回收率为93.2%~97.3%,测定结果的相对标准偏差为1.0%~2.6%(n=6)。该方法简便、快速、准确度高,可为塑料包装材料产品质量监测提供检测方法。The method for determination of tetrabromobisphenol A in plastic packaging materials by ultra performance liquid chromatography–tandem mass spectrometry(UPLC–MS–MS)was established.The samples of plastic packaging material were grinded and crushed,and then were sonicated by the pure methanol,and were concentrated by nitrogen and were determined by UPLC–MS–MS.The content of tetrabromobisphenol A had good linear relations with chromatographic peak area in the range of 2.5–50 ng/g,and the correlation coefficient was 0.999 8,the detection limit was 0.6μg/kg,the limit of quantification was 2.0μg/kg.The average recoveries were 93.2%–97.3%,and the relative standard deviation of determination results was 1.0%–2.6%(n=6).The method is simple,rapid and accurate,it can provide a test method for the quality monitoring of plastic packaging materials.

关 键 词：四溴双酚A UPLC-MS-MS 塑料 

分 类 号：O657.7[理学—分析化学]