Methodological study on endogenous calcium absorptivity using rats and 41Ca tracing  

作　　者：Hui Zhang Liang Dou Xiao-Ming Wang Sheng-Quan Mi Qing-Zhang Zhao Shan Jiang Ming He 

机构地区：[1]China Institute of Atomic Energy, Beijing 102413, China [2]Technical Physics Institute of Heilongjiang Academy of Sciences, Harbin 150086, China [3]Department of Biology, College of Applied Arts and Sciences, Beijing Union University, Beijing 100083, China

出　　处：《Nuclear Science and Techniques》2018年第4期79-82,共4页核技术（英文）

基　　金：supported by the National Nature Science Foundation of China(No.11375272)

摘　　要：Elemental calcium plays an important role in human physiology. In order to study the relationship between Ca-intake, Ca-chemical formulation, and Ca-absorptivity, a balance experiment using a ^(41)Ca tracer technique in SD rats was conducted to measure the endogenous fecal calcium and true absorption of calcium. Apparent absorption of calcium was measured as a control to the endogenous calcium labeling experiment. These results show that by using ^(41)Ca labeled endogenous calcium in vivo, researchers could obtain the true calcium absorption data without extrinsic labeling. Therefore, the method was not affected by the chemical structure or type of calcium supplement and might be used in evaluating the absorptivity of marketed calcium supplements.Elemental calcium plays an important role in human physiology. In order to study the relationship between Ca-intake, Ca-chemical formulation, and Ca-absorptivity, a balance experiment using a ^(41)Ca tracer technique in SD rats was conducted to measure the endogenous fecal calcium and true absorption of calcium. Apparent absorption of calcium was measured as a control to the endogenous calcium labeling experiment. These results show that by using ^(41)Ca labeled endogenous calcium in vivo, researchers could obtain the true calcium absorption data without extrinsic labeling. Therefore, the method was not affected by the chemical structure or type of calcium supplement and might be used in evaluating the absorptivity of marketed calcium supplements.

关 键 词：ENDOGENOUS CALCIUM ABSORPTIVITY 41Ca TRACER Accelerator mass SPECTROMETRY measurement 

分 类 号：TL[核科学技术]