重症胰腺炎早期管饲肠内营养与全肠外营养的疗效比较  

Comparison of enteral nutrition via jejunal tube feeding versus total parenteral nutrition in the treatment of severe acute pancreatitis

作　　者：王文[1] 吴仕平[1] WANG Wen;WU Shiping(Department of General Medicine,Suining Central Hospital,Suining,Sichuan 629000,China)

机构地区：[1]遂宁市中心医院全科医学科,四川遂宁629000

出　　处：《安徽医药》2018年第4期732-734,共3页Anhui Medical and Pharmaceutical Journal

摘　　要：目的比较重症急性胰腺炎经鼻空肠管肠内营养和全肠外营养治疗的临床效果。方法回顾该院2015年1月—2016年6月收治的重症急性胰腺炎患者资料,共64例,根据采用的营养支持方式将其分为肠外营养组(n=34)采用肠外营养,肠内营养组(n=30)采用肠内营养,比较两组的治疗效果。结果肠内营养组血清白蛋白的增长优于肠外营养组,差异有统计学意义(P<0.05);肠内营养组血清淀粉酶恢复正常的时间、平均住院时间均短于肠外营养组(P<0.05);胰腺感染发生率、导管相关感染发生率、多器官衰竭及肺部感染的发生率及病死率两组比较差异无统计学意义(P>0.05)。结论采用经鼻空肠管对重症急性胰腺炎患者进行肠内营养支持,可以更好地改善患者的营养状况。Objective To compare the efficacy of enteral nutrition via jejunal tube feeding versus total parenteral nutrition(TPN)in the treatment of severe acute pancreatitis(SAP).Methods The clinical data of64patients,who were diagnosed as SAP between Jan2015and Jun2016,were analyzed retrospectively.Included patients were divided into two groups based on their nutrition support route.The control group(n=34)was given TPN while the experimental group(n=30)was given enteral nutrition via nasal jejunal tube.The clinical efficacy was compared between the two groups.Results The increase of serum albumin was superior to control group with a significant statistically difference(P<0.05);the restoration time of serum amylase(AMY)and the average hospital length of stay were significant statistically defference(P<0.05),the rate of pancreatic infection,catheter related infection,multiple organ failure and mortality were fewer in the experimental group,but there were no statistically significant difference for all the results above(P>0.05),may due to the risk of aspiration.Conclusions The clinical application of enteral nutrition via jejunal tube feeding in the treatment of severe acute pancreatitis can offer better nutrition support.

关 键 词：重症急性胰腺炎 肠内营养 鼻空肠管 

分 类 号：R576[医药卫生—消化系统]