声敏剂的声动力活性对比研究进展  

Advances in the comparative studies of the sonodynamic activities of sonosensitizers

作　　者：周玲玲 许明玲[1] 刘彬[1] 王晓芳 何玲玲 王新[1] ZHOU Lingling;fXU Mingling;LIU Bin;WANG Xiaofang;HE Lingling;WANG Xin(School of Pharmaceutical Sciences^Liaoning University^Shenyang 110036,China;College of Applied Chemistry,Shenyang University of Chemical Technology,Shenyang 110142,China)

机构地区：[1]辽宁大学药学院,辽宁沈阳110036 [2]沈阳化工大学应用化学学院,辽宁沈阳110142

出　　处：《药学研究》2018年第2期103-107,共5页Journal of Pharmaceutical Research

基　　金：国家自然科学基金(No.21402125);辽宁省教育厅科学研究项目(No.L2016008)

摘　　要：声动力疗法是一种非常有前景的肿瘤治疗方法,声敏剂的研发是声动力疗法(SDT)研究的核心问题。通过对比研究声敏剂的声动力活性,筛选出具有良好声动力活性的声敏剂是设计与开发声敏剂的一条重要途径。本文通过总结各类声敏剂对比研究进展,期望为设计和开发具有良好声动力活性并适用于临床应用的新型声敏剂提供研究思路。Sonodynamic therapy is a promising approach to tumor therapy.The development of sonosensitizer is a key problem in S D T research.lt is an important way to design and develop the sonosensitizer with good sonodynamic activity by comparative studying on their sonodynamic activities.In this paper,the comparative progress of various kinds of sonosensitizers were summarized.lt was hoped to provide research ideas for the design and development of new sonosensitizers with good sonodynamic activity and suitable for clinical application.

关 键 词：声动力疗法 声敏剂 声动力活性 对比研究 

分 类 号：R914.5[医药卫生—药物化学]