河南地区结直肠癌发病特征分析  

Epidemiological Characteristics of Colorectal Cancer in Henan during 2011—2015

作　　者：王福奇[1] 周全博[1] 孙振强[1] 刘金波[1] 杨帅玺 连玉贵 孙献涛[1] 宋军民[1] 袁维堂[1] WANG Fu-qi;ZHOU Quan-bo;SUN Zhen-qiang;LIU Jin-bo;YANG Shuai-xi;LIAN Yu-gui;SUN Xian-tao;SONG Jun-min;YUAN Wei-tang(Department of Anus&Intestine Surgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]郑州大学第一附属医院肛肠外科,河南省郑州市450000

出　　处：《中国全科医学》2018年第3期269-273,共5页Chinese General Practice

基　　金：郑州市科技局项目(153PKJGG162)

摘　　要：目的统计分析河南地区结直肠癌的发病特征,为此地区结直肠癌的临床诊治提供借鉴。方法选择2011年1月—2015年12月河南省郑州大学第一附属医院、河南省人民医院、河南中医药大学第一附属医院、郑州市中心医院经病理诊断且行根治手术治疗的结直肠癌患者8 820例,查询患者出院病历,统计患者临床资料[性别、年龄、有无家族肿瘤史、吸烟(吸烟史>1年,且每天均存在吸烟行为)、有无合并症、肿瘤大小、肿瘤分期、组织类型、大体类型、分化类型、肿瘤位置],分析结直肠癌的发病特征。结果 2011年1月—2015年12月河南地区结直肠癌男女比例为1.269:1,年龄≥60岁与年龄<60岁患者比例为1.096:1,结直肠癌患者分期以Ⅱ、Ⅲ期为主(Ⅱ期3 059例、Ⅲ期3 232例),组织类型以腺癌为主(6 924例),大体类型以溃疡型为主(5 706例),分化类型以中分化为主(7 003例),肿瘤位置以直肠为主(5 029例)。2015年结直肠癌患者例数占所有患者例数的比例为27.1%。结论结直肠癌肿瘤分期集中于Ⅱ、Ⅲ期;分化类型以中分化为主;直肠癌发病率高于结肠癌。Objective To statistically analyze the epidemiological characteristics of colorectal cancer in Henan Province during 2011-2015,with a view to providing a reference for clinical diagnosis and treatment of this disease in this area.Methods We enrolled 8 820 cases who were pathologically diagnosed as colorectal cancer and underwent radical resection of colorectal cancer in the First Affiliated Hospital of Zhengzhou University,Henan Provincial People's Hospital,the First Affiliated Hospital of Henan University of TCM or Zhengzhou Central Hospital from January 2011 to December 2015.By reviewing the medical records,we collected their clinical data〔sex,age,family history of cancer,history of smoking(smoking everyday for over one year),prevalence of complications,size,stage,histological type,gross type,degree of differentiation and location of tumor〕and analyzed the epidemiological characteristics of colorectal cancer.Results In Henan Province from January 2011 to December 2015,the male-female ratio of colorectal cancer was 1.269:1;the ratio of patients aged 60 or older to those younger than 60 was 1.096:1;the stages of colorectal cancer mainly were stageⅡ(3 059 cases)andⅢ(3 232 cases);the main histological type was adenocarcinoma(6 924 cases);ulcer type(5 706 cases)constituted the majority of gross types;most cases had moderately differentiated colorectal cancer(7 003 cases);cancer was located in rectum in most cases(5 029 cases).The incidence of colorectal cancer in 2015 was 27.1%.Conclusion During this period in Henan,colorectal cancer in most cases were stageⅡandⅢ;moderate differentiation with moderate malignancy accounted for the major part;the incidence of rectal cancer was higher than that of colon cancer.

关 键 词：结直肠肿瘤 疾病特征 河南 

分 类 号：R735.34[医药卫生—肿瘤]