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作 者:范励雯 付彤[1] 古林 吴迪[1] 贾泓瑶[1] 宋东[1] FAN Liwen;FU Tong;GU Lin;WU Di;JIA Hongyao;SONG Dong(Department of Breast Surgery,First Hospital,Jilin University,Changchun 130021,Chin)
机构地区:[1]吉林大学第一医院乳腺外科,吉林长春130021
出 处:《吉林大学学报(医学版)》2018年第2期412-415,共4页Journal of Jilin University:Medicine Edition
基 金:吉林省卫生厅科研基金资助课题(3D5171553428)
摘 要:目的:分析1例副乳腺癌(ABC)患者的临床病理特征,探讨ABC的诊断、治疗、手术方式和预后。方法:本例ABC患者行右腋下肿物切除术、右腋下副乳腺切除术和腋窝淋巴结清扫术,未切除患侧乳腺。根据术中快速病理结果确诊为ABC。术后给予8个疗程AC-T(前4个疗程每疗程给予吡柔比星60mg·m-2,环磷酰胺600mg·m-2;后4个疗程每疗程给予多西他赛100mg·m-2;每间隔3周为1个疗程)方案辅助化疗、放疗(给予右侧锁骨上下区、瘤床区预防放疗剂量50Gy/25f后缩野至瘤床区加量至60Gy)、内分泌治疗(他莫昔芬口服至今,每日20mg)。结果:本例患者乳腺彩超及乳腺X线检查均提示右腋下肿物恶性可能性大。临床诊断为右侧腋下ABC。根据NCCN指南给予该患者以手术治疗为主的规范化综合治疗。患者术后16个月恢复良好,生活正常,无上肢功能障碍,未出现患侧上肢淋巴水肿,未出现复发和转移。结论:临床中ABC极其少见,其临床病理特征及治疗方法与乳腺癌相似。若已明确乳腺无病灶,则不必切除患侧乳腺。Objective:To analyze the clinical pathological features of one patient with accessory breast cancer(ABC),and to explore the diagnosis,treatment,operation methods and prognosis of ABC patient.Methods:The patient received right axillary tumor resection,right axillary accessory breast resection and axillary lymph node dissection,didn’t receive resection of breast in the affected side.According to the intraoperative frozen pathological diagnosis,the clinical diagnosis was ABC.After operation,the patient was treated with 8 cycles of AC-T regimen adjuvant chemotherapy(The first four cycles were given pirarubicin 60 mg·m-2,cyclophosphamide 600 mg·m-2 per cycle;the last four cycles were given docetaxel 100 mg·m-2 per cycle;every three weeks was a cycle of treatment),radiation therapy(The radiation dose was 50 Gy/25 f in the upper and lower part of the right collarbone and the tumor bed area,and after retract the tumor bed area was increased to 60 Gy)and endocrine therapy(Tamoxifen was administered at 20 mg per day).Results:The patient’[KG-*3]s breast color ultrasound and mammogram examination indicated that the right axillary mass of the patient was more likely to be malignant.The clinical diagnosis was right axillary ABC.According to the NCCN guide,the patient was treated with the standardized comprehensive treatment based on surgical treatment.16 months after operation,the patient recovered well and had a normal life.There was no upper limb dysfunction and no lateral upper limb lymphedema,and there were no recurrence or metastasis.Conclusion:ABC is extremely rarely seen in clinical practice.The clinical pathological features a
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