甲状腺结节3958例流行病学和临床特点分析  

Epidemiological and clinical characteristics analysis in 3 958 thyroid nodules cases

作　　者：卢燕红[1] 张荣新[1] 王圣应[1] LU Yan-hong;ZHANG Rong-xin;WANG Sheng-ying(Department of Cervical Thoracic Surgery,The Tumor Hosptial of Anhui,Hefei Anhui 230000,China)

机构地区：[1]安徽省肿瘤医院(安徽省立医院西区)颈胸外科,安徽合肥230000

出　　处：《蚌埠医学院学报》2017年第12期1612-1614,共3页Journal of Bengbu Medical College

摘　　要：目的:探讨甲状腺结节(TN)疾病的流行病学和临床特点。方法:回顾性分析3 958例TN病人的临床资料和术后的病理检查结果。结果:2008-2013年TN病例数逐年增加,分别为296、404、542、709、921和1 086例,男女比例约1∶5,右侧1 579例(39.9%)多见,3 185例(80.5%)为良性结节,好发年龄为41~50岁(29.7%),773例(19.5%)为恶性结节,常见于41~50岁(32.8%)。甲状腺癌(TC)中503例(12.7%)为乳头状癌,126例(3.2%)为微小癌,滤泡癌、未分化癌和混合癌均为11例(0.3%),36例(0.9%)为髓样癌。多因素logistic回归分析显示,女性、年龄大(30~60岁)、病程短(<1个月)、有工作、结节直径(≤2 cm)和钙化灶是TC的危险因素(P<0.01)。结论:TN患病率逐年增加,41~50岁的女性是TC的高发人群,年龄、病程、结节大小和钙化灶、职业与TC发病风险有相关性。Objective:To explore the epidemiological and clinical characteristics of thyroid nodules(TN).Methods:The clinical data and postoperative pathology results in 3 958 TN cases were retrospectively analyzed.Results:The number of TN cases gradually increased from 2008 to 2013,which was 296,404,542,709,921 and 1 089 cases,respectively,the ratio of male to female was about 1∶5,1 579 cases(39.9%)located the right side,3 185 cases(80.5%)were benign nodules and 773 cases(19.5%)were malignant nodules,the age ranged from 41 to 50 years old.Among the thyroid carcinoma(TC),the papillary carcinoma in 503 cases(12.7%),microcarcinoma in 126 cases(3.2%),follicular carcinoma in 11 cases(0.3%),anaplastic carcinoma in 11 cases(0.3%),mixed carcinoma in 11 cases(0.3%)and medullary carcinoma in 36 cases(0.9%)were found.Logistic regression analysis showed that the female,elder(30 to 60 years old),short disease course(<1 month),occupation,nodule size(≤2 cm)and nodal calcification were the risk factors of TC.Conclusions:The prevalence of TN increases year by year,the 41 to 50 years old female is high-risk group of TC.The age,course of disease,nodule size,calcification and occupation are related to the TC.

关 键 词：甲状腺肿瘤 甲状腺结节 组织病理学 危险因素 

分 类 号：R736.1[医药卫生—肿瘤]