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作 者:刘兆明 卢勇 Liu Zhaoming;Lu Yong(Ya’an City Chinese Medicine Hospital in Sichuan Province(Ya’an 625000))
出 处:《陕西中医》2018年第4期470-472,共3页Shaanxi Journal of Traditional Chinese Medicine
基 金:四川省雅安市重点科技计划项目(51230309)
摘 要:目的:观察雅安藏茶联合辛伐他汀对高血脂患者血脂水平、颈动脉、治疗依从性的影响。方法:选取高脂血症患者75例进行研究,患者随机分为两组:观察组给予雅安藏茶联合辛伐他丁治疗;对照组给予辛伐他汀治疗。比较两组治疗前后血脂水平、颈动脉内膜中层厚度、内膜斑块面积、易损斑块,统计患者依从性及不良反应发生率,并评定其临床疗效。结果:观察组治疗后的血清总胆固醇、甘油三酯、高密度脂蛋白、颈动脉内膜中层厚度、内膜斑块面积、易损斑块均较治疗前降低(P<0.05),且低于对照组(P<0.05);观察组与对照组总有效率分别为94.74%和86.49%,两组差异具有统计学意义(P<0.05);观察组不良反应率低于对照组。结论:雅安藏茶联合辛伐他汀治疗高脂血症,对患者血脂水平、颈动脉硬化斑块及患者依从性的影响积极,疗效确切,可有效改善患者症状,减轻不良反应,值得临床应用。Objective:To observe the effects of Ya’an tea combined with simvastatin on blood lipidvalue、carotid plaque size and treatment compliance in patients with hyperlipidemia.Methods:75 cases of hyperlipidemia were randomly divided into two groups:the observation group was given Ya’an tea combined with simvastatin to treat;the control group was given simvastatin treatment only.Evaluation of efficacy after 2 months.Results:After the end of treatment,both groups of patients with total cholesterol、triglycerides were reduced(P<0.05),high density lipoprotein cholesterol were increased(P<0.05),carotid atherosclerotic plaque Become smaller(P<0.05),and the observation group of the indicators were significantly better than the control group(P<0.05).The patient compliance and clinical total effective rate of the observation group were higher than the control group(P<0.05),the adverse reaction rate was lower in the observation group than in the control group.Conclusion:Ya’an tea combined with simvastatin in the treatment of the value of blood lipid and carotid atherosclerotic plaque is positive.And patient compliance is increase.It could effectively improve the symptoms of patients and reduce adverse reactions.Itis worthy of clinical application.
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