精神分裂症患者服药信念状况调查及其影响因素研究  

Belief about Medication in Schizophrenia Patients and Its Influencing Factors

作　　者：王正君[1] 周郁秋[1] 孙玉静[1] 高源 WANG Zheng-jun;ZHOU Yu-qiu;SUN Yu-jing;GAO Yuan(Harbin Medical University(Daqing),Daqing 163319,China)

机构地区：[1]哈尔滨医科大学大庆校区,黑龙江省大庆市163319

出　　处：《中国全科医学》2018年第11期1330-1335,共6页Chinese General Practice

基　　金：国家自然科学基金资助项目(71673070);哈尔滨医科大学研究生创新科研项目(YJSCX2016-39HYD);哈尔滨医科大学大庆校区校内科研基金项目(DQXN201611)

摘　　要：目的调查精神分裂症(SZ)患者服药信念状况,探讨其影响因素,为精神科医护人员制定相应干预措施提供参考依据。方法选取2016年5月—2017年5月大庆市第三医院恢复期住院SZ患者112例为调查对象,采用问卷调查方式进行横断面调查,问卷包括一般资料调查表、简明药物影响与信念量表(BEMIB)、阳性与阴性症状量表(PANSS)、功能大体评定量表(GAF)、简易智力状态检查表(MMSE),采用多因素Logistic回归分析影响SZ患者服药信念的相关因素。结果 112例SZ患者BEMIB评分为(29.3±5.1)分,其中对服药持积极信念的有62例,占55.4%;对服药持消极信念的有50例,占44.6%。多因素Logistic回归分析显示,文化程度[OR=5.995,95%CI(1.837,19.562)]、家庭人均月收入[OR=6.110,95%CI(1.918,19.465)]、PANSS一般症状评分[OR=0.790,95%CI(0.629,0.991)]、GAF得分[OR=1.417,95%CI(1.139,1.762)]与SZ患者服药信念有回归关系(P<0.05)。结论 SZ患者服药信念水平较低,文化程度、家庭人均月收入、PANSS一般症状评分、GAF得分是其影响因素。Objective To investigate the belief about medication in schizophrenia(SZ)patients and its influencing factors,so as to provide a reference for psychiatric care providers to deliver appropriate interventions for these patients.Methods We conducted a cross-sectional study in 112 SZ patients in convalescent period who received inpatient treatment in Daqing Third Hospital from May 2016 to May 2017.They were surveyed with Demographic Data Questionnaire,Brief Evaluation of Medication Influences and Beliefs(BEMIB),Positive and Negative Syndrome Scale(PANSS),Global Assessment of Functioning(GAF)and Mini-mental State Examination(MMSE).And the factors associated with belief about medication in SZ patients were analyzed.Results The average BEMIB score was(29.3±5.1)in 112 SZ patients.Sixty-two cases(55.4%)hold positive belief in medication,but 50 cases(44.6%)hold negative belief in medication.Multivariate Logistic regression analysis found that medication belief was affected substantially by educational attainment〔OR=5.995,95%CI(1.837,19.562)〕,monthly household income per person〔OR=6.110,95%CI(1.918,19.465)〕,PANSS general psychopathology score〔OR=0.790,95%CI(0.629,0.991)〕and GAF score〔OR=1.417,95%C(I 1.139,1.762)〕(P<0.05).Conclusion The level of belief about medication is low in SZ patients,which is affected by educational attainment,monthly household income per person,PANSS general psychopathology score and GAF score.

关 键 词：精神分裂症 服药依从性 问卷调查 影响因素分析 

分 类 号：R749.3[医药卫生—神经病学与精神病学]