脉络膜厚度与特发性黄斑前膜的关系研究  

Relationship between choroidal thickness and idiopathic macular epiretinal membrane

作　　者：马君择[1] 权彦龙[1] 杨格强[2] Jun-Ze Ma;Yan-Long Quan;Ge-Qiang Yang(Department of Ophthalmology,the Sencond Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710004,Shaanxi Province,China;Department of Ophthalmology,Xi'an Central Hospital,Xi'an 710004,Shaanxi Province,China)

机构地区：[1]西安交通大学第二附属医院眼科,中国陕西省西安市710004 [2]中国陕西省西安市中心医院眼科,710004

出　　处：《国际眼科杂志》2018年第4期734-736,共3页International Eye Science

摘　　要：目的:探讨脉络膜厚度和特发性黄斑前膜(idiopathic macular epiretinal membrane,IMEM)发生发展的关系。方法:回顾性分析2014-01/2016-12期间我院就诊的IMEM患者48例48眼,并选取同期体检健康者50例的右眼进行对照,比较IMEM组患眼、健眼及对照组黄斑中心凹脉络膜厚度(subfoveal choroidal thickness,SFCT)水平,随访观察术后IMEM患者患眼及健眼SFCT水平变化,并分析术后脉络膜厚度和最佳矫正视力的相关性。结果:术前IMEM组患眼SFCT(362.22±40.75μm)明显较对侧健眼(410.56±38.45μm)及对照组右眼(420.73±39.63μm)低,且对侧健眼较对照组右眼低,差异均有统计学意义(均P<0.05)。IMEM组患者术后1wk患眼和健眼SFCT与术前比较差异均无统计学意义(P>0.05),而术后1mo患眼和健眼SFCT均显著升高,和术前相比差异有统计学意义(P<0.05),此后SFCT值趋于稳定,而术后1mo患眼和健眼比较差异无统计学意义(P>0.05);术前不同SFCT值患者术后BCVA≥0.5患者构成比差异有统计学意义(P<0.05),且SFCT值>380μm组术后BCVA≥0.5患者构成比明显较<320μm组和320～380μm组高,经Fisher确切概率法分析,差异有统计学意义。经Pearson分析,IMEM患者术后脉络膜厚度和术后最佳矫正视力存在正相关性(r=0.629,P<0.05)。结论:脉络膜变薄可能是IMEM的重要诱因。AIM:To investigate the relationship between the thickness of choroid and the development of idiopathic macular epiretinal membrane(IMEM).METHODS:A retrospective analysis on 48 cases(48 eyes)of idiopathic macular epiretinal membrane patients(the IMEM group)was taken in our hospital from January 2014 to December 2016,and 50 right eyes in 50 healthy persons with physical examination were selected the control group,comparison on subfoveal choroidal thickness(SFCT)levels of sicked eyes,normal eyes in IMEM group and the control group were made,postoperative SFCT level change of sicked eyes in IMEM patients and normal eyes were investigated via follow-up,and analysis on correlation between postoperative choroidal thickness and the best corrected visual acuity was taken.RESULTS:The SFCT of sicked eyes in IMEM group 362.22~40.75m was significantly lower than that of the contralateral eyes(410.56~38.45m)and the right eyes of the control group(420.73~39.63m),and data of the contralateral eyes was lower than right eyes of the control group,distinct difference was shown between groups(P<0.05).The IMEM group's SFCT of sicked eyes and normal eyes at postoperative 1wk had no significant difference with that before operation(P>0.05),and at postoperative 1mo,SFCT of sicked eyes and normal eyes evidently increased,showing sharp difference compared with that before operation(P<0.05).After that,the SFCT value stabilized,but there was no obvious difference between the sicked eyes and healthy eyes at postoperatively 1mo(P>0.05).The numbers of patients whose postoperative BCVA≥0.5 with different preoperative SFCT values had statistically significant differences(P<0.05),and those with BCVA≥0.5 of SFCT values>380m were significantly higher than those with<320m and 320m-380m groups.Fisher exact probability analysis showed that the differences were significant.Pearson analysis showed that there was a positive correlation between the postoperative choroid thickness and the best corrected visual acuity of IMEM group(r=0.629,P<0.05).CONCLU

关 键 词：特发性黄斑前膜 脉络膜厚度 关系 

分 类 号：R774.5[医药卫生—眼科]