肠易激综合征患者睡眠质量和精神心理状况的调查  

Investigation on Sleep Quality and Psychological Status in Patients With Irritable Bowel Syndrome

作　　者：王彬[1] 赵威[1] 许梦雀 华建平[3] 张秋瓒[4] 刘艳迪[5] 王东旭[6] 唐艳萍 王邦茂[1] WANG Bin;ZHAO Wei;XU Mengque;HUA Jianping;ZHANG Qiuzan;LIU Yandi;WANG Dongxu;TANG Yanping;WANG Bangmao(Department of Gastroenterology and Hepatology,Tianjin Medical University General Hospital,Tianjin,300052;Department of Gastroenterology,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou;Department of Gastroenterology,Tianjin First Center Hospital,Tianjin;Department of Gastroenterology,Tianjin 4th Centre Hospital,Tianjin;Department of Gastroenterology,Tianjin Union Medical Center,Tianjin;Department of Gastroenterology,the 254 th Hospital of the People’s Liberation Army,Tianjin;Department of Gastroenterology,Tianjin Hospital ITCWN Nankai Hospital,Tianjin)

机构地区：[1]天津医科大学总医院消化内科,300052 [2]浙江大学医学院附属邵逸夫医院消化内科 [3]天津市第一中心医院消化内科 [4]天津市第四中心医院消化内科 [5]天津市人民医院消化内科 [6]中国人民解放军第254医院消化内科 [7]天津市中西医结合医院南开医院消化内科

出　　处：《胃肠病学》2018年第3期161-165,共5页Chinese Journal of Gastroenterology

基　　金：国家自然科学基金(81370492);国家自然基金青年项目(81600425)

摘　　要：背景:肠易激综合征(IBS)是一种常见的功能性胃肠病(FGIDs),可降低患者的生活质量,并对精神心理产生一定影响。目的:探讨IBS和IBS重叠其他FGIDs患者的睡眠障碍和精神心理异常状况,并初步分析睡眠障碍发生的危险因素。方法:对2014年1月—2014年12月天津市6家医院就诊的FGIDs患者进行问卷调查,采用匹兹堡睡眠质量指数量表(PSQI)评估睡眠质量,焦虑自评量表(SAS)和抑郁自评量表(SDS)分别评估焦虑、抑郁状况,二分类Logistic回归分析法初步探讨IBS重叠其他FGIDs患者睡眠障碍的影响因素。结果:共1 117例FGIDs患者完成问卷,其中单纯IBS患者32例(2.9%),IBS重叠其他FGIDs患者113例(10.1%)。IBS组睡眠障碍、精神心理异常以及两者同时存在的比例分别为59.4%、93.8%和59.4%,IBS重叠组分别为82.3%、95.6%和78.8%。性别、年龄和症状严重程度可能是IBS重叠组睡眠障碍的危险因素(P=0.014,P=0.049,P=0.025)。结论:IBS和IBS重叠患者均伴有不同程度的睡眠障碍和(或)精神心理异常,性别、年龄和症状严重程度可能是IBS重叠组患者睡眠障碍的危险因素。Background:Irritable bowel syndrome(IBS)is a commonly seen functional gastrointestinal disorders(FGIDs),and can reduce the quality of life and has some effects on patients’psychology.Aims:To investigate the disorder of sleep and psychological status in patients with IBS and IBS overlapping other FGIDs,and to analyze their risk factors.Methods:Questionnaires were conducted among FGIDs patients from January 2014 to December 2014 in 6 hospitals at Tianjin.Pittsburgh sleep quality index(PSQI)was used to assess sleep quality,anxiety and depression were assessed by self-rating anxiety scale(SAS)and self-rating depression scale(SDS),respectively.Two-factor Logistic regression analysis was used to analyze the risk factors of sleep disorder in patients with IBS overlapping other FGIDs.Results:A total of 1 117 patients with FGIDs completed the questionnaires,including 32 IBS patients(2.9%)and 113 patients(10.1%)with IBS overlapping other FGIDs.The percentages of sleep disorder,psychological disorder,and combination of the two were 59.4%,93.8%and 59.4%in IBS group,respectively;and 82.3%,95.6%and 78.8%in IBS overlapping other FGIDs group,respectively.Gender,age and severity of symptoms were the risk factors of sleep disorder in patients with IBS overlapping other FGIDs(P=0.014,P=0.049,P=0.025).Conclusions:Both IBS patients and IBS overlapping other FGIDs patients are associated with varying degrees of sleep disorder and/or psychological disorder.Gender,age and severity of symptoms may be the risk factors of sleep disorder in IBS overlapping other FGIDs patients.

关 键 词：肠易激综合征 睡眠障碍 精神障碍 问卷调查 

分 类 号：R574.4[医药卫生—消化系统]