大骨节病与骨关节炎流行病学特点对比分析  

A comparative analysis of epidemiological characteristics between Kaschin-Beck disease and osteoarthritis

作　　者：张盼 王溪 郭雄[1] ZHANG Pan;WANG Xi;GUO Xiong(Department of Public Health,Medical School of Xi'an Jiaotong University,Key Laboratory of Genes Related Diseases of Ministry of Education,Xi'an 710061,China)

机构地区：[1]西安交通大学医学部公共卫生系,环境与疾病相关基因教育部重点实验室,陕西西安710061

出　　处：《国外医学（医学地理分册）》2018年第2期119-123,共5页Foreign Medical Sciences：Section of Medgeography

摘　　要：大骨节病是一种慢性地方性骨关节病,严重影响病区3~12岁儿童的生长发育。骨性关节炎是严重危害老年人的退行性骨关节病,2种疾病的发病原因至今仍不清楚且目前均无有效的治疗措施。因此,了解2种疾病流行病学的特征对预防大骨节病和骨关节炎显得尤为重要。结合国内外的相关文献,阐述了大骨节病与骨关节炎的流行病学特征的异同点以及2种疾病的预防、治疗及发病机制。Kaschin-Beck disease is a chronic endemic osteoarthropathy,which seriously affects the skeleton development of children aged 3 to 12 years.Osteoarthritis is characterized by progressive articular cartilage degeneration,which seriously jeopardizes the elderly s health.At present,the pathogenesis of both diseases is still unknown and there are no effective treatment measures.Therefore,it is particularly important to explore the features of the two diseases so as to prevent them.This paper reviewed the domestic and overseas literatures,summarized the similarities and differences between the two diseases,hoping to provide scientific basis for their prevention,treatment and pathogenesis research.

关 键 词：大骨节病 骨关节炎 流行病学 

分 类 号：R155[医药卫生—营养与食品卫生学]