脑出血再发预测因素分析  

Analysis of predictors of Recurrent Cerebral Hemorrhage

作　　者：吴顺琴[1] 浮荣莉[1] 李宏丽[1] WU Shunqin;FU Rongli;LI Hongli(Huaihe Hospital of Henan University,Kaifeng 475000,China)

机构地区：[1]河南大学淮河医院,河南开封475000

出　　处：《河南大学学报（医学版）》2018年第1期28-31,共4页Journal of Henan University:Medical Science

基　　金：开封市科技攻关计划项目(1403023)

摘　　要：[目的]鉴别和比较脑出血再发的预测因子,评估它们对再发性脑出血的相对作用。[方法]选取2014年7月至2015年12月在河南大学淮河医院治疗的192例脑出血再发患者为病例组。对照组为按照同医院、同性别、同民族、同年龄(相差≤5岁)、同时间段(出院时间间隔≤7 d)的要求进行1∶1配对的192例脑出血首发患者。比较两组患者社会人口学、疾病相关因素、用药情况及发生时间的差异,观察脑出血再发的危险因素。[结果]首次脑出血后再发间隔时间为2 mon^15 a,平均(3.6±0.41)a。单因素分析显示高血压、血压控制不良、糖尿病、未规律服用降压药的患者更易再发脑出血(P<0.05)。多因素条件Logistic回归分析显示,高血压(OR值3.373,95%CI为1.435~5.399)、血压控制不良(4.027,2.449~6.620)、糖尿病(1.938,1.193~3.149)是脑出血患者再发发生风险的独立预测因素(P<0.05)。[结论]高血压、血压控制不良、糖尿病会增加脑出血患者再发风险。〔Objective〕To identify and compare the predictors of recurrent cerebral hemorrhage and its relative contribution to recurrent cerebral hemorrhage.〔Methods〕192 cases of recurrent cerebral hemorrhage in Huaihe Hospital of Henan University from July 2014 to December 2015 were selected as the case group.Control group according to the same hospital,sex,ethnic,age(difference less than 5 years)and the same time(discharge time interval for 7 days or less)requirements of 1∶1 matching the 192 cases of cerebral hemorrhage for the first time.The differences of social demography,disease related factors,drug use and occurrence time were compared in the two groups,and the risk factors of recurrent cerebral hemorrhage were observed.〔Results〕The recurrence time of the first cerebral hemorrhage was from 2 months to 15 years,with an average of(3.6+0.41)years.Univariate analysis showed that high blood pressure,bad blood pressure control,diabetes and unregular antihypertensive drugs were more likely to recur cerebral hemorrhage(P<0.05).Multifactorial conditional Logistic regression analysis showed that hypertension(OR=3.373,95%CI 1.435-5.399),poor blood pressure control(4.027,2.449-6.620)and diabetes(1.938,1.193-3.149)were independent predictors of the risk of recurrent cerebral hemorrhage(P<0.05).〔Conclusion〕Hypertension,poor control of blood pressure,diabetes can increase the risk of recurrent cerebral hemorrhage.

关 键 词：脑出血 再发性脑出血 危险因素 

分 类 号：R743.34[医药卫生—神经病学与精神病学]