Metapex糊剂应用于乳牙根管治疗效果的Meta分析  

Effect of Metapex paste on root cancal therapy of deciduous teeth:a Meta-analysis

作　　者：何艳艳 姚华[1] 姚亚男[1] 汪国华[1] HE Yanyan;YAO Hua;YAO Yanan;WANG Guohua(Stomatology Department,The First Affiliated Hospital,Zhejiang University,Hangzhou,Zhejiang 310003,China)

机构地区：[1]浙江大学医学院附属第一医院口腔内科,浙江杭州310003

出　　处：《预防医学》2018年第4期359-363,共5页CHINA PREVENTIVE MEDICINE JOURNAL

基　　金：莱菔子素对镍诱导人正常口腔上皮细胞氧化应激的抑制作用(LY14H140001)

摘　　要：目的评价Metapex糊剂应用于乳牙根管治疗的效果。方法以"Metapex糊剂""乳牙根管治疗"等为关键词,检索中国知网、万方数字化期刊全文数据库、维普中文科技期刊数据库等中文数据库;以"Metapex""deciduous teeth"等为关键词,检索PubMed、Medline等英文数据库。查找关于Metapex糊剂与临床常用的氧化锌碘仿糊剂、氢氧化钙糊剂等应用于乳牙根管治疗的随机对照研究,时间范围为建库至2017年8月。采用RevMan 5.3软件进行Meta分析。结果共检索到248篇文献,最终纳入12个随机对照试验。Meta分析结果显示,Metapex糊剂组术后1年的成功率高于氧化锌碘仿糊剂组(RR=1.11,95%CI:1.01~1.22);Metapex糊剂组术后6个月及1年的成功率均高于氢氧化钙糊剂组(RR_(6个月)=1.06,95%CI:1.03~1.09;RR_(1年)=0.17,95%CI:1.03~1.10);Metapex糊剂组与氧化锌组术后6个月成功率差异无统计意义(RR=1.13,95%CI:1.00~1.27)。结论Metapex糊剂能提高乳牙根管治疗成功率,是较为理想的乳牙根管充填材料。Objective To evaluate the effect of Metapex for root canal therapy of deciduous teeth.Methods Based on the key words“Metapex paste”and“Root canal therapy of deciduous teeth”,the Chinese database,such as China national knowledge infrastructure,Wanfang database and Weipu database were retrieved.Based on the key words“Metapex”and“deciduous teeth”,the English databases such as PubMed and Medline were retrieved.Collecting random controlled trials about Metapex paste with root canal therapy of deciduous teeth from the beginning of their establishment to August 2017.Do Meta analysis using Rev Man 5.3 software for homogeneous studies,calculating risk ratio(RR)and 95%confidence interval(CI).Results Twelve studies were included.Meta analysis showed that Metapex was more effective in root canal therapy of deciduous teeth compared with zinc oxide eugenol iodoform paste after 1 year(RR=1.11,95%CI:1.01-1.22);The clinical effectiveness of Metapex paste was better than calcium hydroxide after 6 months and 1 year(RR6 mouths=1.06,95%CI:1.03-1.09;RR1 year=0.17,95%CI:1.03-1.10);There was no obvious difference between Metapex and ZOE after 6 months(RR=1.13,95%CI:1.00-1.27).Conclusion Metapex paste can improve the success rate on root canal therapy of deciduous teeth,is a more ideal root canal filling material of deciduous teeth.

关 键 词：METAPEX糊剂 乳牙 根管治疗 META分析 

分 类 号：R788[医药卫生—口腔医学]