8例胸腺鳞癌患者临床分析  

Clinical analysis of 8 cases of thymic squamous cell carcinoma

作　　者：史文松 付校[1] 刘东雷[1] 陈小放[1] 刘帅帅 魏创业 崔广晖[1] Shi Wensong;Fu Xiao;Liu Donglei;Chen Xiaofang;Liu Shuaishuai;Wei Chuangye;Cui Guanghui(Department of Thoracic Surgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]郑州大学第一附属医院胸外科,河南郑州450000

出　　处：《河南医学研究》2018年第4期585-587,共3页Henan Medical Research

摘　　要：目的分析原发性胸腺鳞癌的临床特征及诊疗方法。方法回顾性分析8例原发性胸腺鳞癌患者的临床资料。结果 8例患者胸部CT均显示肿瘤与周围大血管关系密切。手术完整切除者5例,其中切除侵犯肺组织2例,姑息切除3例。术后病理Masaoka分期:Ⅳ期6例,Ⅰ期1例,Ⅱ期1例。术后行辅助治疗者6例。随访期间有3例发生肺部转移,未行二次手术。手术完整切除患者1年生存率为100%(5/5)。结论原发性胸腺鳞癌早期临床症状不典型,术前增强CT及穿刺活检是明确诊断的主要手段,扩大切除术与放化疗联合的综合治疗方案为胸腺鳞癌的主要治疗方法。Objective To analyze the clinical features and diagnosis and treatment of primary thymic carcinoma.Methods The clinical data of 8 patients with primary thymic carcinoma were retrospectively analyzed.Results All 8 patients’chest CT images showed that the tumor and the surrounding large blood vessels were closely related.There were 5 cases of complete resection,including 2 cases of excision of lung tissue,and 3 patients accepated palliative resection.According to postoperative Masaoka staging,there were 6 cases of stageⅣ,1 case of stageⅠ,1 case of stageⅡ.Six patients accepted postoperative adjuvant therapy.During the follow-up period,there were 3 cases of lung metastases without reoperation.The 1-year survival rate was 100%(5/5)for patients who underwent complete surgical resection.Conclusion Primary thymic squamous cell carcinoma’s early clinical symptoms is not typical.preoperative enhanced CT and biopsy are the main methods for the diagnosis of primary thymic carcinoma.The combination of extended resection,chemotherapy and radiotherapy is the main method for the treatment of thymic squamous cell carcinoma.

关 键 词：胸腺鳞癌 临床特征 诊断 治疗 

分 类 号：R736.3[医药卫生—肿瘤]