胃肠道间质瘤45例临床分析  

Clinical Analysis of 45 Cases with Gastrointestinal Stromal Tumor

作　　者：马永宝[1] 孙飞[1] 申庆宏[1] 周建农[2] MA Yong-bao;SUN Fei;SHEN Qing-hong;ZHOU Jian-nong(Department of General Surgery,Xuyi Hospital of Traditional Chinese Medicine,Xuyi,Jiangsu Province,211700 China;Department of Gastrointestinal Surgery,Jiangsu Tumor Hospital,Nanjing,Jiangsu Province,210009 China)

机构地区：[1]江苏省盱眙县中医院普外科,江苏盱眙211700 [2]江苏省肿瘤医院胃肠外科,江苏南京210009

出　　处：《系统医学》2017年第22期117-119,共3页Systems Medicine

摘　　要：目的分析胃肠道间质瘤(GIST)的临床特征及预后情况,以期对读者及时有效诊治GIST有所帮助。方法回顾性分析该院2012年1月—2015年6月收治的GIST45例的临床资料。结果该组患者均痊愈出院。术后随访40例,平均随访24个月。有8例分别于手术后18~31个月复发。其中,有2例作了2次手术,最后死于肠梗阻、恶病质。其中有6例出现不良反应,另37例无不良反应,其中9例配合了伊马替尼(Imati Ilib)靶向治疗,手术联合靶向治疗疗效要高于单纯手术治疗(P<0.05)。结论手术切除仍然是治疗GIST的首选方法,术后配合伊马替尼靶向治疗可取得更好的效果。Objective To analyze the clinical features and prognosis of GIST in order to provide help for the effective and timely treatment of patients.Methods The clinical data of 45 cases of GIST patients admitted and treated in our hospital from January 2012 to June 2015 were retrospectively analyzed.Results All patients were cured and discharged,and 40 cases were followed up,24 months on average,and 8 cases reoccurred in 18 months and 31 months after surgery,and 2 cases underwent 2 operations,but died due to intestinal obstruction and emaciation,besides,6 of them had adverse reactions,and the other 37 had no adverse reactions,and 9 cases used the ImatiIlib targeted therapy,and the curative effect of operation combined with targeted therapy was higher than that of simple operation(P<0.05).Conclusion The operation resection is still the primary method in treatment of GIST,and the effect of operation combined with ImatiIlib targeted therapy can obtain a better effect.

关 键 词：胃肠道间质瘤 预后 治疗 

分 类 号：R735.2[医药卫生—肿瘤]