肝硬化患者血清钙、磷及钙调节激素检测的临床意义  

Clinical significance of serum calcium, phosphate and calcium regulation hormone in patients with cirrhosis

作　　者：张婷 ZHANG Ting(Laboratory Department,the Hospital of Sanyuan County,Xianyang 713800,China)

机构地区：[1]三原县医院检验科,陕西咸阳713800

出　　处：《临床医学研究与实践》2018年第10期109-110,共2页Clinical Research and Practice

摘　　要：目的分析肝硬化患者血清钙、磷及钙调节激素检测的临床意义。方法选取2016年7月至2017年6月我院收治的150例肝硬化患者,依据Child-pugh分级分为A级组(n=65)、B级组(n=50)及C级组(n=35);选取同期50例健康体检者作为常规组。比较四组受检者的血清钙、磷及钙调节激素水平。结果 C级组患者的血清钙水平明显低于常规组、A级组及B级组(P<0.05);四组受检者的血磷水平比较,差异无统计学意义(P>0.05)。与常规组、A级组及B级组比较,C级组患者的CT与25-(OH)D_3水平明显较低,PTH明显较高(P<0.05)。结论肝硬化患者多伴有血清钙磷与钙调节激素代谢紊乱,并随着病情的发展而逐渐加剧,临床上可对肝硬化患者血清钙、磷及钙调节激素进行检测,便于对实际肝功能损害情况进行详细分析,从而指导疾病的治疗。Objective To analyze the clinical significance of serum calcium,phosphate and calcium regulation hormone in patients with cirrhosis.Methods A total of 150 cirrhosis patients admitted in our hospital from July 2016 to June 2017 were selected and divided into grade A group(n=65),grade B group(n=50)and grade C group(n=35)according to childpugh grodes.A total of 50 physical examiners in the same period were selected as the routine group.The serum calcium,phosphate and calcium regulation hormone were compared between the four groups.Results The serum calcium level of the grade C group was lower than that of the routine group,the grade A group and the grade B group(P<0.05).There were no significant differences in serum phosphate between the four groups(P>0.05).Compared with the routine group,the grade A group and the grade B group,the levels of CT and 25-(OH)D3 were lower,and the PTH level was higher in the grade C group(P<0.05).Conclusion Patients with cirrhosis are often accompanied by disorder of serum calcium and phosphate,and calcium regulatory hormone metabolism,and gradually increased with the development of the disease.The serum calcium,phosphorus and calcium regulation hormone can be detected in patients with cirrhosis.It is convenient for detailed analysis of the actual liver function damage,so as to guide the treatment of the disease.

关 键 词：钙调节激素 血清钙、磷 肝硬化 

分 类 号：R575.2[医药卫生—消化系统]