经皮血管内成形及支架置入术治疗脑梗死伴重度颈动脉狭窄的研究  

The feasibility and safety of percutaneous transluminal angioplasty and stent implantation in the treatment of cerebral infarction with severe carotid stenosis

作　　者：刘海涛[1] 张淑玲[1] 白宏英[2] 郭耀强 LIU Haitao;ZHANG Shulin;BAI Hongying;GUO Yaoqiang(Department of Neurology,Zhengzhou People's Hospital,Zhengzhou 450000;Second Affiliated Hospital of Zhengzhou University,Zhengzhou 450014,China;Department of Neurology,Chest Hospital of Henan,Zhengzhou 450000,China)

机构地区：[1]郑州人民医院神经内科一病区,河南郑州450000 [2]郑州大学第二附属医院,河南郑州450014 [3]河南省胸科医院神经内科,河南郑州450000

出　　处：《中国实用神经疾病杂志》2018年第8期819-821,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨脑梗死伴颈动脉狭窄患者采用经皮血管内成形及支架置入术治疗的可行性与安全性。方法选择2016-05—2017-05的脑梗死伴重度颈动脉狭窄的69例患者为研究对象,分为对照组(34例)与观察组(35例)。对照组只是单纯药物治疗,观察组采用经皮血管内成形及支架置入术治疗,比较2组患者治疗效果与安全性。结果观察组NIHSS评分降低幅度比对照组高,2组间比较差异具有统计学意义(P<0.05)。观察组脑梗死复发率与病死率分别为2.86%、2.86%,对照组脑梗死复发率与病死率分别为17.65%、11.76%。观察组复发率与病死率明显低于对照组,2组间比较差异具有统计学意义(P<0.05)。结论脑梗死伴重度颈动脉狭窄患者采用经皮血管内成形及支架置入术治疗,有助于减少患者复发率与病死率。经皮血管内成形及支架置入术治疗脑梗死伴重度颈动脉狭窄疾病具有较高的可行性与安全性。Objective To explore the feasibility and safety of endothelial and stent implantation in patients with cerebral infarction and carotid artery stenosis.Methods 69 cases of cerebral infarction with severe carotid stenosis were selected from May 2016 to May 2017 as the study subjects and they were divided into control group(34 cases)and observation group(35 cases).The control group was only treated with drugs,and the observation group was treated with percutaneous endovascular forming and stent implantation.The efficacy and safety of the two groups were compared.Results The NIHSS score in the observation group was significanlty lower than that in the control group(P<0.05).The incidence and mortality of cerebral infarction in the observation group were 2.86%and 2.86%,respectively,and the mortality rate was 17.65%and 11.76%,respectively.The recurrence rate and mortality were significantly lower in the observation group than in the control group(P<0.05).Conclusion Percutaneous endovascular and stent implantation can reduce the recurrence rate and mortality in patients with cerebral infarction and severe carotid artery stenosis.Therefore,it is feasible and safe in the treatment of cerebral infarction with severe carotid artery stenosis.

关 键 词：经皮血管内成形 支架置入术 脑梗死伴重度颈动脉狭窄 可行性 安全性 

分 类 号：R743.33[医药卫生—神经病学与精神病学]