血清降钙素原联合C-反应蛋白对肝癌患者介入手术后感染的诊断价值  

Analysis of diagnostic value of serum procalcitonin combined with C-reactive protein for infection after interventional operation treatment in patients with liver cancer

作　　者：刘健[1] 李海珠[1] 甘瑞伟 姚艺雄[1] 全毅[1] LIU Jian;LI Haizhu;GAN Ruiwei;YAO Yixiong;QUAN Yi(Department of Clinical Laboratory,The First People's Hospital of Zhaoqing City,Guangdong,Zhaoqing 526020,China)

机构地区：[1]肇庆市第一人民医院检验科,广东肇庆526020

出　　处：《包头医学院学报》2018年第4期46-47,73,共3页Journal of Baotou Medical College

摘　　要：目的:探讨血清降钙素原(PCT)与C-反应蛋白(CRP)对肝癌介入手术后感染的诊断作用。方法:选择163例肝癌行介入手术患者为研究对象,根据其术后是否感染分为感染组51例、未感染组112例,对所有患者检测PCT、CRP水平,并进行对比。结果:感染组PCT、CRP水平均较未感染组高(P<0.05),PCT+CRP的敏感度、特异度、阳性预测值较CRP高(P<0.05),PCT与PCT+CRP的特异度、阴性预测值、阳性预测值比较差异无统计学意义(P>0.05),PCT+CRP敏感度高于PCT(P<0.05)。结论:肝癌介入手术后感染风险较高,PCT联合CRP检测具有较高的特异性与敏感性,值得临床推广应用。Objective:To probe into the diagnostic effects of serum procalcitonin(PCT)and C-reactive protein(CRP)for infection after interventional operation treatment in patients with liver cancer.Methods:163 patients with liver cancer who underwent interventional surgery were selected as the research objects,and were grouped according to the occurrence of postoperative infection,51 cases in the infection group and 112 cases in the non-infection group.Then,the levels of PCT and CRP in all subjects were detected and compared.Results:The levels of PCT and CRP in the infection group were higher than those in the non-infection group,and the difference was statistically significant(P<0.05);the sensitivity,specificity and positive predictive value of PCT+CRP were higher than those of CRP(P<0.05);the specificity,negative predictive value and positive predictive value of PCT and PCT+CRP were not significantly different(P>0.05);the sensitivity of PCT+CRP was higher than that of PCT(P<0.05).Conclusion:The risk of infection after interventional operation in patients with liver cancer is higher,and detection of PCT combined with CRP is of higher specificity and sensitivity,thus it is worthy to be promoted in the clinical treatment.

关 键 词：血清降钙素原 C-反应蛋白 肝癌介入术 诊断 

分 类 号：R735.7[医药卫生—肿瘤]