彩色多普勒超声评分和血流阻力指数结合糖类抗原125在卵巢肿瘤中的诊断价值  

The clinical diagnostic value of color doppler ultrasonography and blood flow resistance index (RI) combined with tumor marker CA125 in the diagnosis of benign and malignant ovarian tumors

作　　者：马彩叶[1] 刘夏天[1] 李星云[1] 陈兴美[1] 江珍珍[1] Ma Caiye;Liu Xiatian;Li Xingyun;Chen Xingmei;Jiang Zhenzhen(Department of Ultrasound,the People′s Hospital of Shaoxing,Shaoxing 312000,China)

机构地区：[1]浙江绍兴市人民医院超声科,312000

出　　处：《中国临床保健杂志》2018年第2期179-181,共3页Chinese Journal of Clinical Healthcare

基　　金：浙江省医药卫生一般研究计划(2015KYA220)

摘　　要：目的探析彩色多普勒超声评分和血流阻力指数(RI)结合糖类抗原125(CA125)在良、恶性卵巢肿瘤诊断中的临床价值。方法选取卵巢肿瘤患者119例,根据肿瘤的良、恶性分为良性肿瘤组和恶性肿瘤组。良性卵巢肿瘤患者71例为良性肿瘤组,恶性卵巢肿瘤患者48为恶性肿瘤组,采用彩色多普勒超声评分和RI结合CA125进行诊断,对其临床诊断价值作出评价。评价指标包括Finkler超声评分、CA125水平、RI指数等。结果良性肿瘤组患者的CA125水平为(28.59±18.54)u/m L,RI指数0.63±0.13,Finkler平均分数(3.94±1.38)分,恶性肿瘤组分别为(495.42±37.28)u/m L、8.46±1.39、(0.47±0.15)分,均P<0.05。以手术病理验证的结果为参照,良性肿瘤组、恶性肿瘤组的联合诊断准确率分别为95.8%,97.9%,与超声单独诊断的80.3%、83.3%,RI的78.9%、79.2%,CA125的74.6%、77.1%比较,均P<0.05。结论彩色多普勒超声和RI结合CA125对卵巢肿瘤的诊断准确率高。Objective To evaluate the clinical value of color Doppler ultrasonography and blood flow resistance index(RI)combined with tumor marker CA125 in the diagnosis of benign and malignant ovarian tumors.Methods A total of 119 patients with ovarian cancer treated in our department were divided into two groups according to the benign and malignant tumors.Benign ovarian tumor patients in 71 cases for benign group,malignant ovarian tumor patients in 48 for malignant group.Evaluation indicators included Finkler ultrasound score,CA125 level,RI index and so on.Results The level of CA125 in benign group was(28.59±18.54)u/mL,RI index(0.63±0.13),Finkler mean score(3.94±1.38)points,malignant group:(495.42±37.28)u/mL,8.46±1.39,(0.47±0.15)points,two groups of comparison were all P<0.05.The diagnostic accuracy of benign group and malignant group were 95.8%and 97.9%respectively,ultrasonic diagnosis were 80.3%and 83.3%respectively,RI were 78.9%and 79.2%respectively,CA125 were 74.6%and 77.1%,respectively(all P<0.05).Conclusion Color doppler ultrasonography and RI combined with CA125 have high accuracy in the diagnosis of ovarian cancer,which also is better for distinguishing benign and malignant tumor.

关 键 词：卵巢肿瘤 超声检查 多普勒 彩色 血流动力学 CA125 

分 类 号：R737.31[医药卫生—肿瘤]