儿童朗格汉斯细胞组织细胞增生症13例临床特征分析  

Analysis of Clinical Features of 13 Cases of Children with Langerhans' Cell Hyperplastic Disease

作　　者：许春华 安美玉[1] 陈芬[1] 姚彤[1] 罗新辉[1] XU Chun-hu;AN Mei-yu;CHEN Fen;YAO Tong;LUO Xin-hui(Department of Pediatrics,Xinjiang Uygur Autonomous People's Hospital,Urumqi,Xinjiang,830001 China)

机构地区：[1]新疆维吾尔自治区人民医院儿科,新疆乌鲁木齐830001

出　　处：《中外医疗》2017年第35期33-34,56,共3页China & Foreign Medical Treatment

摘　　要：目的探讨儿童朗格汉斯细胞组织细胞增生症(LCH)的临床特点,提高诊治水平。方法方便2013年1月—2017年6月在该院确诊的13例朗格汉斯细胞组织细胞增生症患儿进行回顾性分析。结果单系统组LCH 6例,多系统组LCH 7例,两组的性别构成比差异无统计学意义,多系统组发病年龄显著小于单系统组。儿童多累及骨(61.5%)、皮肤(53.8%)、肺(46.2%)、肝(46.2%)、脾(23.1%)、耳(30.8%)等。结论 LCH临床表现多样,病情轻重不一,明确诊断规范治疗可改善预后。Objective To study the clinical features of Langerhans'cell Hyperplastic disease and improve the diagnosis and treatment level.Methods 13 cases of children with LCH diagnosed in our hospital from January 2013 to June 2017 were convenient analyzed.Results There were 6 cases in the single system group and 7 cases in the multiple systems group,and the difference in the gender ratio between the two groups was not statistically significant,and the onset age in the multiple systems group was younger than that in the single system group,and the children are mainly involved in bone(61.5%),skin(53.8%),lung(46.2%),liver(46.2%),spleen(23.1%)and era(30.8%).Conclusion The clinical manifestations of LCH are multiple,and the severity of the disease is different,and the prognosis can be improved after clearing the diagnosis standards.

关 键 词：朗格汉斯细胞组织细胞增生症 儿童 骨骼 皮肤 

分 类 号：R74[医药卫生—神经病学与精神病学]