颌面部间隙感染并存糖尿病患者的临床特征分析  

Analysis of Clinical Characteristics of Patients with Maxillofacial Space Infection and Diabetes Mellitus

作　　者：周昊[1] 杨忠昕 夏鑫 费伟[1,2] Zhou Hao;Yang Zhongxin;Xia xin;Fei wei(Department of Maxillofacial Surgery,Sichuan Academy of Medical Sciences&Sichuan Provincial People's Hospital,Chengdu 610072,China;Southwest Medical University,Luzhou 646000,China)

机构地区：[1]四川省人民医院颌面外科,成都610072 [2]西南医科大学,泸州646000

出　　处：《成都医学院学报》2018年第2期162-165,共4页Journal of Chengdu Medical College

基　　金：国家自然科学基金资助项目(No:81600852)

摘　　要：目的分析颌面部间隙感染并存糖尿病患者的临床特征,指导颌面部间隙感染合并糖尿病患者的临床治疗。方法选取2015年1月至2017年5月四川省人民医院颌面外科收治的83例颌面部间隙感染患者的临床资料进行回顾性分析。根据是否并存糖尿病,分为糖尿病组(n=37)和非糖尿病组(n=46)。对口腔颌面部间隙感染患者的性别、年龄、感染来源、受累间隙数目、实验室指标、并发症发生率、住院天数和治疗方案进行分析。结果在口腔颌面部间隙感染患者中,糖尿病组患者年龄更大(P=0.006);牙源性感染为最常见的感染来源;糖尿病组患者感染更容易累及2个以上间隙(P=0.001),更容易发生并发症(P=0.013),住院时间更长(P=0.008),入院后使用更高级抗生素(P<0.001),两联用药的可能性更大(P<0.001)。结论口腔颌面部间隙感染并存糖尿病患者与未并存糖尿病患者的临床特征有着较大差异,应予以高度重视,严格控制血糖,及时切开引流,选择合适的抗生素治疗。Objective To analyze the clinical characteristics of patients with maxillofacial space infection(MSI)and diabetes mellitus and provide guidances for the clinical treatment.Methods The clinical data of 83 MSI patients treated in Sichuan Province People's Hospital from January of 2015 to May of 2017 were analyzed retrospectively.According to whether patients had diabetes mellitus nor not,they were divided into the diabetes group(n=36)and non-diabetes group(n=47).The clinical characteristics including gender,age,source of infection,number of involved spaces,laboratory indexes,incidence of complications,length of hospital stay,and therapeutic regimen were analyzed statistically.Results Among the 83 MSI patients,the patients in the diabetes group were significantly older(P=0.006).Odontogenic infection was the most common source of infection.The patients in the diabetes group tended to have more than two involved spaces(P=0.001),more complications(P=0.013),longer hospital stay(P=0.008),more use of advanced antibiotics after admission(P<0.001),and higher likelihood of being treated with the combination of two drugs(P<0.001).Conclusion There are significant differences in clinical characteristics between the MSI patients with diabetes mellitus and those without diabetes mellitus,which should be taken seriously with strict control of blood sugar,timely incision and drainage,and appropriate selection of antibiotic treatment.

关 键 词：颌面部 间隙感染 糖尿病 临床特征 

分 类 号：R782.3[医药卫生—口腔医学]