基于TOPAS质子放疗剂量的模拟研究  

Simulation of proton radiation dose based on TOPAS

作　　者：谢聪[1] 林辉[1] 景佳[1] 许良凤[2] 胡敏[2] XIE Cong;LIN Hui;JING Jia;XU Liangfeng;HU Min(School of Electronic Science and Applied Physics,Hefei University of Technology,Hefei 230009,China;School of Computer and Information,Hefei University of Technology,Hefei 230009,China)

机构地区：[1]合肥工业大学电子科学与应用物理学院,安徽合肥230009 [2]合肥工业大学计算机与信息学院,安徽合肥230009

出　　处：《合肥工业大学学报（自然科学版）》2018年第4期553-556,共4页Journal of Hefei University of Technology：Natural Science

基　　金：中国科学院战略性先导科技专项资助项目(XDA03040000)

摘　　要：文章利用蒙特卡罗粒子输运软件TOPAS,模拟研究了质子束在均匀介质和非均匀介质中的剂量分布特点和质子束扩展Bragg峰的合成方法,并对解析算法中常用于非均匀介质修正的等效路径法的精度进行了验证。该文工作为今后开展质子剂量实验测量和临床治疗剂量的研究提供了一定的参考。Using Monte Carlo particle transport software TOPAS,simulations on the dose distribution characteristics of proton beam in homogeneous medium and heterogeneous medium and the synthesis method of proton beam spread-out Bragg peak(SOBP)are carried out,and the precision of equivalent path method commonly used in the inhomogeneous medium modification in parsing algorithm is verified.The study can provide theoretical guidance for the experimental measurement of proton dose and the research on clinical therapeutic dose in the future.

关 键 词：质子放疗 蒙特卡罗模拟 等效路径法 扩展Bragg峰 

分 类 号：R730.55[医药卫生—肿瘤]