肝细胞癌普美显磁共振增强成像与病理分级的相关性研究初探  

Correlation of Gd-EOB-DTPA-enhanced MRI with Pathologic Grading in Hepatocellular Carcinoma

作　　者：郭天畅 伍彩云 温运雄 叶文卫 彭森 GUO Tian-chang;WU Cai-yun;WEN Yun-xiong(Department of Radiology,the Third People's Hospital of Dongguan,Dongguan 523321,Guangdong Province,China)

机构地区：[1]广东省东莞市第三人民医院医学影像科,广东东莞523321

出　　处：《中国CT和MRI杂志》2018年第3期63-65,共3页Chinese Journal of CT and MRI

基　　金：东莞市医疗卫生单位科技计划一般项目立项;立项编号(20131051010074)

摘　　要：目的探讨肝细胞癌普美显(GdEOB-DTPA)MRI增强成像与病理分级的相关性。方法对20位患者的25个肝细胞癌灶进行回顾性分析。所有病例均行MRI平扫、普美显动态增强扫描及肝胆期扫描,根据肝胆期病灶的信号强度分为三组:低信号、混杂信号和等信号,并与术后标本的病理分级进行对比、分析。结果 25例肝细胞癌肝胆期的信号强度与病理分级间有显著的差异。肿瘤的大小与病理分级无明显差异。结论肝细胞癌的普美显MRI增强成像肝胆期信号强度与病理分级存在明显的相关性,可据此初步判断HCC的病理分级。建议临床怀疑肝细胞癌的病人影像检查中选择应用普美显行MRI增强检查。Objective To investigate the Correlation of Gd-EOB-DTPA-enhanced MRI with Pathologic Grading in Hepatocellular Carcinoma.Methods Twenty patients with twenty-five hepatocellular lesions were evaluated retrospectively.All of the patients had MRI scan,Gd-EOB-DTPA dynamic enhanced scan and hepatobiliary stage enhanced scan.Hepatobiliary phase images on Gd-EOB-DTPA-enhanced MRI were classified into 3 groups:low,mixed signal or iso.Furthermore,correlations between MRI findings and pathological grade for each hepatocellular lesions were performed and statistically evaluated.Results There was a significant correlation between pathological grade and signal intensity in the hepatobiliary phase in 25 cases of hepatocellular carcinoma.There was no significant correlation between the size of the tumor and the pathological grade.Conclusion Signal intensity in the hepatobiliary phase correlated with histological grade.We may have a new way to preliminary judge the pathological grade of HCC according to Gd-EOB-DTPA-enhanced MRI.Gd-EOB-DTPA-enhanced MRI is recommended to apply in patients who were suspected with hepatocellular carcinoma.

关 键 词：肝细胞癌 磁共振 GD-EOB-DTPA 

分 类 号：R735.7[医药卫生—肿瘤]