磁共振全身弥散成像在恶性肿瘤诊断中的应用研究  

The Application of Magnetic Resonance Whole Body Diffusion Weighted Imaging in the Diagnosis of Malignant Tumors

作　　者：王丽华[1] 管霞[1] 孟磊[1] 宋东喜 WANG Li-hua;GUAN Xia;MENG Lei(Department of MRI Room,Puyang people's hospital,Puyang 457000,Henan Province,China)

机构地区：[1]河南省濮阳市人民医院磁共振室,河南濮阳457000

出　　处：《中国CT和MRI杂志》2018年第2期122-125,共4页Chinese Journal of CT and MRI

摘　　要：目的研究磁共振全身弥散成像(WB-DWI)在恶性肿瘤诊断中的应用价值。方法选取我院2013年2月至2016年8月临床疑似恶性肿瘤患者38例设置为观察组,选取同期在我院接受体检的正常健康志愿者12例设置为对照组,对两组均进行磁共振全身弥散成像检查,并于一周内对病变处行常规磁共振成像(MRI)检查,分析两组WB-DWI成像特点。结果 38例临床疑似恶性肿瘤患者最终诊断为恶性肿瘤的30例,良性病变8例,WB-DWI诊断恶性肿瘤29例,漏诊1例,WB-DWI诊断恶性肿瘤的敏感度为93.33%,特异度为87.50%,假阴性率为12.50%,假阳性率为6.67%,阳性预测值为96.67%,阴性预测值为77.78%,符合率为92.11%。良性肿瘤病灶的最大平均弥撒系数值(ADC)、最小平均ADC值、平均ADC值较恶性肿瘤均显著较高(P<0.05)。结论 WB-DWI在体部性肿瘤筛查中有一定的临床价值,对良恶性肿瘤分辨率较高,能帮助临床尽早制定肿瘤治疗方案,及早采取有效的治疗措施,最大程度的延长患者生存期。Objective To study the value of magnetic resonance whole body diffusion weighted imaging(WB-DWI)in the diagnosis of malignant tumors.Methods From February 2013 to August 2016,38 patients with suspected malignant tumors in our hospital were selected as the observation group,and 12 normal healthy volunteers were selected as the control group at the same time.Both groups were examined by WBDWI,and the lesions were examined by conventional magnetic resonance imaging(MRI)within one week.The WB-DWIcharacteristics of the two groups were analyzed.Results Among 38 patients with suspected malignant tumors,there were 30 cases diagnosed with malignant tumors and 8 cases with benign lesions.WB-DWI diagnosed malignant tumors in 29 cases and 1 case was not diagnosed.The sensitivity,specificity,false negative rate,false positive rate the positive predictive value,negative predictive value and the coincidence rate of WB-DWI in the diagnosis of malignant tumors were 93.33%,87.50%,12.50%,6.67%,96.67%,77.78%and 92.11%.The maximum mean diffusion coefficient(ADC)value,the minimum mean ADC value and the mean ADC value of benign tumors were significantly higher than those of malignant tumors(P<0.05).Conclusion WB-DWI is of certain clinical value in the screening of tumors in body,and the accuracy in the differential diagnosis of benign and malignant tumors is high.It can help the development of clinical treatment and prolong the survival time of the patients to the maximum extent.

关 键 词：磁共振 全身弥散成像 恶性肿瘤 诊断 

分 类 号：R73[医药卫生—肿瘤] R445.2[医药卫生—临床医学]