硫糖铝联合奥美拉唑治疗胃溃疡合并胃出血的临床分析  

The clinical analyzing of treatment gastric ulcer with gastrorrhagia by Sucralfate combined with Omeprazole

作　　者：曾清洲 张小燕[2] ZENG Qing-zhou;ZHANG Xiao-yan(The Emergency Center,the People′s Hospital in Nanxiong City,Guangdong Province,Nanxiong 512400,China;Department of internal Medicine,the People′s Hospital in Nanxiong City,Guangdong Province,Nanxiong 512400,China)

机构地区：[1]广东省南雄市人民医院急救中心,广东南雄512400 [2]广东省南雄市人民医院内科,广东南雄512400

出　　处：《中国当代医药》2018年第10期157-159,共3页China Modern Medicine

摘　　要：目的探讨硫糖铝联合奥美拉唑治疗胃溃疡合并胃出血的临床效果。方法选取2016年2月~2017年3月我院收治的80例胃溃疡合并胃出血患者作为研究对象,按照治疗措施的不同将其分为对照组(40例)与观察组(40例)。对照组患者单独采用奥美拉唑治疗,观察组患者采用硫糖铝联合奥美拉唑治疗。比较两组患者的呕血停止时间、大便OB试验阴性时间、腹部疼痛消失时间、不良反应发生率和治疗总有效率。结果观察组患者的呕血停止时间[(1.7±0.2)d]、大便OB试验阴性时间[(4.6±1.2)d]、腹部疼痛消失时间[(2.2±0.4)d]均短于对照组[(2.3±0.4)、(6.5±1.3)、(3.6±0.5)d],差异有统计学意义(P<0.05)。观察组患者的不良反应发生率(7.5%)均低于对照组(25.0%),临床治疗总有效率(95.0%)高于对照组(80.0%),差异均有统计学意义(P<0.05)。结论使用硫糖铝联合奥美拉唑治疗胃溃疡合并胃出血患者,临床症状改善时间缩短,疗效明显,不良反应少,值得临床推广应用。Objective To clinical effect of treatment gastric ulcer with gastrorrhagia by Sucralfate combined with Omeprazole.Methods A total of 80 patients of gastric ulcer with gastrorrhagia treated in our hospital from February 2016 to March 2017 were selected as subjects and divided into control group(40 cases)and observation group(40 cases)by different treatment method.The patients in the control group were treated with Omeprazole alone,and the patients in the observation group were treated with Sucralfate combined with Omeprazole.The hematemesis stop time,stool OB test negative time,abdominal pain disappeared time,the incidence of adverse reactions and the total effective rate of two group were compared.Results The hematemesis stop time([1.7±0.2]d),stool OB test negative time([4.6±1.2]d)and abdominal pain disappeared time([2.2±0.4]d)of observation group were shorter than the control group([2.3±0.4],[6.5±1.3],[3.6±0.5]d),and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the observation group(7.5%)was lower than that in the control group(25.0%),and the total effective rate(95.0%)was higher than the control group(80.0%),the differences were statistically significant(P<0.05).Conclusion The clinical symptoms improve time is shorten,the clinical effect is obviously,adverse reactions are little of gastric ulcer with gastrorrhagia patients treated by Sucralfate combined with Omeprazole.It is worth to be used.

关 键 词：硫糖铝 奥美拉唑 胃溃疡 胃出血 

分 类 号：R573.1[医药卫生—消化系统]