高纤维饮食对克罗恩病患者的肠功能及与健康相关的生活质量的影响  

Effect of high-fiber diet on intestinal function and health-related quality of life in Crohn′s disease patients

作　　者：刘海琴[1] Liu Haiqin(Department of Gastroenterology,Central Hospital of Baoji,Shannxi 721008,China)

机构地区：[1]陕西省宝鸡市中心医院消化内科,721008

出　　处：《山西医药杂志》2018年第7期757-759,共3页Shanxi Medical Journal

摘　　要：目的探讨高纤维饮食对克罗恩病患者的肠功能及与健康相关的生活质量的影响。方法选择2014年5月至2017年5月我院收治的克罗恩病患者60例进行研究。采用随机数字表法将患者分为2组,每组各30例。对照组患者进行常规克罗恩病饮食干预,观察组在此基础上加以全麦麸皮谷物及低糖饮食。以炎性肠病问卷(IBDQ)和部分Harvey Bradshaw指数(pHBI)作为评价指标,以问卷调查的形式收集数据。结果 2组患者干预后IBDQ均一定程度的改善,但观察组与对照组相比改善程度随着时间的推移而变大(P<0.05)。IBDQ评分≥32分的变化被认为是临床显著反应,观察组的平均IBDQ评分增加了(42±4)分,而对照组仅增加了(21±4)分。2组pHBI评分随时间显著降低,干预组患者在第4周时在该指数上评分为"0",表明幸福感强,没腹痛或便后障碍的持续症状。相比之下对照组患者在第4周时都对pHBI评分为"3",表明这些个体仍然表现腹痛和大便量增多等影响幸福感的因素。结论高纤维饮食可改善克罗恩病患者的肠功能,提高患者健康相关的生活质量。Objective To investigate the effect of high-fiber diet on the intestinal function and health-related quality of life in Crohn's disease patients.Methods From May 2014 to May 2017,60 cases of Crohn's disease admitted to our hospital were studied.The patients were divided into two groups using random number table method,30 cases in each group.Patients of the control group received conventional Crohn's disease diet intervention,the observation group received whole wheat bran cereal and low-sugar diet on the basis of control's diet.The IBDQ and some of the Harvey Bradshaw Index(pHBI)were used as evaluation indicators to collect data in the form of questionnaires.Results After intervention,IBDQ was improved in both groups,but the improvement in the observation group and the control group increased over time(P<0.05).The change of IBDQ score greater than or equal to 32 was considered clinically significant,and the average IBDQ score of the observation group increased(42±4),while the control group increased only(21±4).The two groups of pHBI scores significantly decreased over time,and the intervention group scored"0"on the index in the fourth week,indicating that there was no strong feeling of happiness,abdominal pain or persistent symptoms of post-ambulation disorder.In contrast,patients in the control group rated pHBI as"3"in the fourth week,indicating that these individuals still showed signs of abdominal pain and increased defecation and other factors affecting happiness,such as increased abdominal pain and increased stool volume.Conclusion High fiber diet improves bowel function in patients with Crohn's disease and improves the health-related quality of life of patients.

关 键 词：饮食习惯 克罗恩病 肠功能 生活质量 

分 类 号：R574.62[医药卫生—消化系统]