3种口腔护理方法对慢性牙周炎患者牙周临床指标的影响  

A primary study of the effects of different oral care methods on periodontitis

作　　者：高鹏[1] 姚茹[1] 荆玉洁[2] GAO Peng;YAO Ru;JING Yu-jie(Department of Stomatology,No.451 Hospital of PLA,Xi′an 710054,China)

机构地区：[1]解放军第451医院口腔科,陕西西安710054 [2]解放军第451医院内镜中心,陕西西安710054

出　　处：《牙体牙髓牙周病学杂志》2018年第4期237-239,224,共4页Chinese Journal of Conservative Dentistry

摘　　要：目的:观察3种口腔护理方法对慢性牙周炎患者牙周临床指标的影响。方法:选择牙周基础治疗1个月的中、重度慢性牙周炎患者60例,随机分为3组(n=20),A组用奥硝唑+复方氯己定漱口;B组用30 m L/L过氧化氢棉签擦拭;C组用生理盐水漱口。检查并记录基线和1、3个月的探诊深度(PD)、菌斑指数(PLI)、附着丧失(AL)以及龈沟液(GCF)量,并采用酶联免疫吸附法检测GCF中基质金属蛋白酶(MMP-3)的水平。结果:与基线相比,在口腔护理后1、3个月,A、B组PD、PLI、GCF量、MMP-3水平均显著降低(P<0.05),AL仅A组在3个月时显著降低(P<0.05);而C组的各项牙周临床指标均无明显变化(P>0.05)。结论:奥硝唑+复方氯己定漱口和30 m L/L过氧化氢擦拭的口腔护理方式对慢性牙周炎患者的牙周临床指标有明显抑制作用,且奥硝唑+复方氯己定漱口的疗效显著。AIM:To study the effects of different oral care methods on the clinical indexes of periodontitis(CP).METHODS:60 cases with CP were divided into 3 groups(n=20),ornidazole+chlorhexidine(group A),peroxide(group B)and saline(group C)were respectively used for the subjects as oral care in the groups.Before and after nursing treatment for 1 and 3 months probing depth(PD),plaque index(PLI),attachment lose(AL)and gingival crevicular fluid(GCF)of the subjects were measured,the content of matrix metalloproteinases3(MMP-3)in GCF were detected by ELISA.RESULTS:After nursing treatment,the level of PD,PLI,content of GCF and MMP-3 in GCF were significantly reduced(P<0.05)in group A and group B,the level of AL only reduced(P<0.05)in Group A 3 months after treatment.The content of GCF and MMP-3 in GCF were significantly reduced(P<0.05)in the same period in group A and group B.CONCLUSION:The best nursing treatment for CP is metronidazole+nitrofurazone.

关 键 词：口腔护理 牙周炎 牙周临床指标 龈沟液 基质金属蛋白酶 

分 类 号：R781.4[医药卫生—口腔医学]