双载药静电纺丝膜的制备及抑菌效果观察  

Preparation of Electrospun Membranes Loaded Double Drugs and Observation of Its Antimicrobial Effect

作　　者：杜凤霞[1] 王月飞[1] 姚淑娟[1] 吕丽艳[1] 刘秀财[1] 张凤娇[1] 郭俊杰[1] 蒋丽艳[1] 王慧[1] 张浩[1] DU Feng-xia;WANG Yue-fei;YAO Shu-juan;Lu Li-yan;LIU Xiu-cai;ZHANG Feng-jiao;GUO Jun-jie;JIANG Li-yan;WANG Hui;ZHANG Hao(Qiqihar Medical University,Qiqihar,Heilongjiang,161006,China)

机构地区：[1]齐齐哈尔医学院,黑龙江齐齐哈尔161006

出　　处：《动物医学进展》2018年第7期67-69,共3页Progress In Veterinary Medicine

基　　金：黑龙江省教育厅科研项目(2016-KYYWF-0839)

摘　　要：以聚乙烯醇(PVA)和海藻酸钠(SA)为载体,万古霉素和头孢吡肟作为模型药物,制备具有可吸收性能的抗菌静电纺丝膜。以静电纺丝膜的抑菌效果作为指标,结果表明,制备的双载药静电纺丝膜载药均匀,可纺性好,具有良好的抑菌性能。The antibacterial electrospun membranes with absorbable properties were prepared by using polyvinyl alcohol(PVA)and sodium alginate(SA)as carrier,vancomycin and cefepime as model drugs.The results showed that the electrospun membranes loaded double drug are homogeneous and have good spinnability and good antibacterial property.

关 键 词：双载药 聚乙烯醇 海藻酸钠 静电纺丝膜 抑菌 

分 类 号：S859.5[农业科学—临床兽医学] S859.798[农业科学—兽医学]