胆管细胞癌局部治疗的研究现况及进展  

Present situation and advance in cholangiocarcinoma locoregional therapy

作　　者：程家敏 刘泽[1] 董政 董景辉[1] 李茵茵 曾珍[1] 杨新瑞 陆荫英[1] CHENG Jia-min;LIU Ze;DONG Zheng;DONG Jing-hui;LI Yin-yin;ZENG Zhen;YANG Xin-rui;LU Yin-ying(Comprehensive Liver Cancer Center,302 Military Hospital of China,Beijing 100039,China)

机构地区：[1]解放军第三〇二医院肝脏肿瘤诊疗与研究中心,北京100039

出　　处：《传染病信息》2018年第3期245-247,254,共4页Infectious Disease Information

基　　金：国家自然科学基金项目(7172207;81702389)

摘　　要：胆管细胞癌(cholangiocarcinoma,CCA)是我国常见的恶性肿瘤之一,其发病率仍处于上升趋势。目前对部分CCA患者局部病灶行R0外科切除术,依旧是可能根治的惟一方案。而对于出现转移的CCA患者来说,系统化疗及支持治疗的抗肿瘤效果不理想,对于生存时间改善有限,而且还伴有较为明显的毒副作用。因此,应该探索更多的局部治疗手段应用于CCA患者的临床治疗,并使之获益。Cholangiocarcinoma(CCA)is one of the common primary liver malignancy with an increasing incidence in China.Up to now,R0 resection has been regarded as the only potentially curative treatment for local lesion of CCA patients.The results of systemic chemotherapy and best supportive care in CCA patients with metastatic disease are disappointing due to limited improvement of overall survival and apparent resultant toxic side effects.Therefore,more locoregional therapies should be increasingly applied for patients'benefits.

关 键 词：胆管细胞癌 手术切除 局部治疗 热消融治疗 纳米刀 立体定向体部放射治疗 

分 类 号：R735.8[医药卫生—肿瘤]