大型听神经瘤显微手术治疗的效果观察  

Observation on the effect of microsurgical treatment of large acoustic neuroma

作　　者：张鹏 戴宜武 秦家振 张鹏飞 曾旭 吴翠莹 ZHANG Peng;DAI Yiwu;QIN Jiazhen;ZHANG Pengfei;ZENG Xu;WU Cuiying(The PLA Army General Hospital,Beijing 100700,China)

机构地区：[1]解放军陆军总医院,北京100700

出　　处：《中国医药科学》2018年第12期14-16,共3页China Medicine And Pharmacy

基　　金：国家自然科学基金青年项目(81401031;81601085)

摘　　要：目的观察大型听神经瘤显微手术治疗的效果。方法选取我院2010年4月~2017年1月72例大型听神经瘤患者,所有患者均经枕下乙状窦后入路行听神经瘤显微手术切除,观察患者的临床治疗效果与术后不良事件的发生情况。结果肿瘤全切除患者共有62例,全切率为86.11%,次全切7例,占9.72%;大部切除3例,占4.16%。术中有64例患者面神经解剖保留,占88.89%;有50例患者术后1周面神经功能保留,占69.44%。术后肿瘤部位血肿1例,占1.38%;无术后死亡患者。结论利用枕下乙状窦后入路显微手术方法能够有效提升患者的治愈率,并有效降低术后并发症与不良反应,值得临床推广。Objective To observe the effect of microsurgical treatment of large acoustic neuroma.Methods From April 2010 to January 2017,72 patients with large acoustic neuroma in our hospital were selected.All patients underwent microsurgical resection of acoustic neuroma through suboccipital retrosigmoid approach.The clinical efficacy and postoperative adverse events were observed.Results There were 62 patients who underwent total tumor resection,the total resection rate was 86.11%,and 7 patients underwent subtotal resection,accounting for 9.72%,3 cases were resected,accounting for 4.16%.64 patients(88.89%)had facial nerve anatomical preservation during the operation.50 patients had facial nerve function preservation one week after surgery,accounting for 69.44%.One case(1.38%)had hematoma at the tumor site after operation.There were no postoperative deaths.Conclusion The use of the approach of the suboccipital retrosigmoid sinus approach can effectively improve the cure rate of the patients,and effectively reduce the postoperative complications and adverse reactions,which is worthy of clinical promotion.

关 键 词：大型听神经瘤 显微手术 临床疗效 肿瘤全切除 

分 类 号：R739.4[医药卫生—肿瘤]