急性脑梗死阿司匹林联合氯吡格雷及大剂量阿司匹林抗血小板治疗的临床观察  

Clinical observation of aspirin combined with clopidogrel and large-dose aspirin for acute cerebral infarction

作　　者：汲晶[1] 李景春 龙海泳 杜文华[1] Ji Jing;Li Jingchun;Long Haiyong;Du Wenhua(The Integrated Traditional Chinese Medicine and Western Medicine Hospital of Changping District in Beijing City 102208)

机构地区：[1]北京市昌平区中西医结合医院,102208

出　　处：《中国社区医师》2018年第20期19-20,共2页Chinese Community Doctors

摘　　要：目的:探讨阿司匹林联合氯吡格雷以及大剂量阿司匹林治疗急性脑梗死的临床疗效。方法:收治急性脑梗死患者108例,随机分为3组。A组给予阿司匹林常规治疗,B组给予氯吡格雷联合阿司匹林治疗,C组给予大剂量阿司匹林治疗,比较3组治疗前后NIHSS评分、总有效率。结果:B组、C组治疗后NIHSS评分明显低于A组,治疗总有效率明显高于A组,差异具有统计学意义(P<0.05)。结论:氯吡格雷联合阿司匹林治疗急性脑梗死疗效优于单用阿司匹林,大剂量阿司匹林临床疗效优于常规剂量。Objective:To explore the clinical effect of aspirin combined with clopidogrel and large-dose aspirin in the treatment of acute cerebral infarction.Methods:108 cases of patients with acute cerebral infarction were divided into three groups randomly.Group A was given routine aspirin treatment,group B was treated with clopidogrel and aspirin,and group C was treated with large-dose of aspirin,the NIHSS score and total effective rate among the three groups before and after treatment were compared.Results:The NIHSS scores in group B and group C were significantly lower than those in group A,the total effective rate was significantly higher than that of group A,and the difference was statistically significant(P<0.05).Conclusion:The clinical effect of clopidogrel combined with aspirin in the treatment of acute cerebral infarction was superior to aspirin alone,and the clinical effect of large-dose aspirin was better than that of conventional dose.

关 键 词：急性脑梗死 氯吡格雷 阿司匹林 

分 类 号：R743.3[医药卫生—神经病学与精神病学]