小梁切开联合周边虹膜切除术治疗色素性青光眼  

Treatment of Pigmentary Glaucoma with Trabeculotomy and Peripheral Iridectomy

作　　者：李木 徐玲娟 周雄武 LI Mu;XU Lingjuan;ZHOU Xiongwu(Department of ophthalmology,Tongji Hospital,Tongji medical college,Huazhong University of Science and Technology-Wuhan 430030,China)

机构地区：[1]华中科技大学同济医学院附属同济医院,武汉430030

出　　处：《实用医学杂志》2018年第13期2169-2171,2176,共4页The Journal of Practical Medicine

基　　金：国家自然科学基金面上项目(编号:81770921)

摘　　要：目的评估色素性青光眼患者接受小梁切开联合周边虹膜切除术治疗效果。方法对小梁切开联合周边虹膜切除术的色素性青光眼患者8例(15眼)行手术前后眼压、房角开放距离500,小梁网虹膜间面积500和虹膜曲率比较。结果相较术前眼压(26.63±3.61)mm Hg,术后3 d(17.58±3.93)mm Hg,1周(18.39±2.88)mm Hg和1个月(17.63±1.99)mm Hg眼压显著降低(所有P<0.05);同时相比术前房角开放距离500(1.317±0.393)mm,小梁网虹膜间面积500(0.498±0.199)mm2和虹膜曲率(-0.034±0.016)mm,术后房角开放距离500术后3 d(0.782±0.200)mm,1周(0.798±0.233)mm,1个月(0.807±0.227)mm,小梁网虹膜间面积500术后3 d(0.296±0.087)mm2,1周(0.303±0.098)mm2,1个月(0.307±0.100)mm2和虹膜曲率术后3 d(0.008±0.002)mm,1周(0.010±0.011)mm,1个月(0.010±0.012)mm变化显著(所有P<0.05)。结论小梁切开联合周边虹膜切除术不仅可以解除反向瞳孔阻滞,避免色素播散的继续发展,还能及时有效控制色素性青光眼患者眼压。Aim To investigate the changes in intraocular pressure(IOP)and anterior chamber parame-ters after trabeculotomy and peripheral iridectomy in patients with pigmentary glaucoma.Methods Fifteen eyes from 8 patients with pigmentary glaucoma were included in this study.The pre-and post-operation IOP,angle opening distance at 500μm from scleral spur(AOD500),trabecular-iris space area at 500μm from scleral spur(TISA500),iris concavity(IC)were compared.Results Compared with pre-operation IOP(26.63±3.61)mmHg,the post-operation IOP(17.58±3.93)mmHg for 3 days,(18.39±2.88)mmHg for 1 week,(17.63±1.99)mmHg for 1 month decreased significantly(P<0.05,respectively).Furthermore,compared with pre-operation AOD500(1.317±0.393)mm,TISA500(0.498±0.199)mm2,IC(-0.034±0.016)mm,the post-operation AOD500(0.782±0.200)mm for 3 days,(0.798±0.233)mm for 1 week,(0.807±0.227)mm for 1 month,TISA500(0.296±0.087)mm2 for 3 days,(0.303±0.098)mm2 for 1 week,(0.307±0.100)mm2 for 1 month,and IC(0.008±0.002)mm for 3 days,(0.010±0.011)mm for 1 week,(0.010±0.012)mm for 1 month were also decreased significantly(P<0.05,respectively).Conclusions For patients with pigmentary glaucoma,trabecu-lotomy and peripheral iridotomy could prevent the pigment from continuing to disperse,and reduce IOP.

关 键 词：色素性青光眼 小梁切开术 周边虹膜切除术 反向瞳孔阻滞 

分 类 号：R779.6[医药卫生—眼科]