体脂肪含量与儿童青少年高血压关系  

Relationship between percent body fat and hypertension in children and adolescents

作　　者：徐仁应[1] 周一泉[1] 张晓敏[1] 陈之琦[1] 万燕萍[1] XU Renying;ZHOU Yiquan;ZHANG Xiaomin;CHEN Zhiqi;WAN Yanping(Department of Clinical Nutrition,Ren Ji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200127,China)

机构地区：[1]上海交通大学医学院附属仁济医院临床营养科,上海200127

出　　处：《临床儿科杂志》2018年第7期481-485,共5页Journal of Clinical Pediatrics

基　　金：雅培HOPE基金会项目(No.AFINS-HOPE-2013-06);浦东新区卫计委课题(No.PW2016D-05)

摘　　要：目的探讨儿童青少年体脂肪含量与高血压的关系。方法采用横断面研究方法纳入5 144名6~13岁学生(男2 649名、女2 495名)为研究对象;采集身高、体质量、血压,以生物电阻抗法检测体脂肪含量;以收缩压或舒张压任一项高于同年龄同性别血压P95为高血压。采用ROC曲线分析体脂肪含量预测高血压的切点值;以多因素logistic回归分析体脂肪含量对高血压的影响。男生体脂肪含量分布以10岁年龄组为高峰,而女生体脂肪含量分布则与年龄增长一致。男生和女生体脂肪含量预测高血压的切点值分别为18.0%和18.8%。控制年龄、性别、身高和体质量,男生体脂肪含量高于该预测切点值,则高血压风险增加51%(OR=1.51,95%CI:1.04~2.07);女生体脂肪含量超过切点值,则高血压风险增加53%(OR=1.53,95%CI:1.00~2.34)。体脂肪含量预测男生高血压的效能[ROC曲线下面积(AUC)=0.649]低于BMI(AUC=0.695),差异有统计学意义(P<0.01);体脂肪含量预测女生高血压的效能(AUC=0.644)与BMI(AUC=0.650)的差异无统计学意义(P>0.05)。结论男生和女生体脂肪含量预测高血压的切点值分别为18.0%和18.8%。BMI预测儿童高血压时仍优于体脂肪含量。Objectives To explore the relationship between percent body fat and hypertension in children and adolescents.Method A cross-sectional study was conducted in 5144 children(2649 boys and 2495 girls)aged 6~13 years.Body height,body weight and blood pressure of all the children were collected,and percent body fat(PBF)was detected by bioelectrical impedance analysis.Either Systolic or diastolic blood pressure above ninety-fifth percentile of that of the same age and gender is considered hypertension.The cut point value of PBF for predicting hypertension was analyzed by ROC curve.Multivariate logistic regression was used to evaluate the effect of PBF on hypertension.Result The distribution of PBF peaked in ten-yearold boys while it increases with age in girls.The cut-off values of PBF in boys and girls for predicting hypertension were 18%and 18.8%respectively.After controlling for the effects of age,sex,height and body weight,the risk of hypertension increased by 51%(OR=1.51,95%CI:1.04~2.07)in boys and 53%(OR=1.53,95%CI:1.00~2.34)in girls when the PBF was higher than the cut-off point.PBF was less effective than BMI for predicting hypertension in boys(area under curve for BMI 0.695 vs PBF 0.649,P<0.01)while there was no significant difference between the PBF and BMI in girls(area under curve for BMI 0.650 vs PBF 0.644,P>0.05).Conclusion The cut-off values of PBF in boys and girls for predicting hypertension were 18%and 18.8%respectively.BMI is still superior to PBF for predicting hypertension in children.

关 键 词：体脂肪含量 体质指数 高血压 ROC曲线 儿童 青少年 

分 类 号：R725.4[医药卫生—儿科]