不同骨挤压手术设计对种植术后骨改建的影响  

Effect of Different Bone Condensation Methods on Bone Remodeling after Implantation

作　　者：朱宇驰 王雨薇 郭晓东 包崇云[1] 王了 ZHU Yu-chi;WANG Yu-wei;GUO Xiao-dong;BAO Chong-yun;WANG Liao(State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases,Department of Oral and Maxillofacial Surgery,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China)

机构地区：[1]口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院口腔颌面外科,四川成都610041

出　　处：《口腔医学研究》2018年第7期717-720,共4页Journal of Oral Science Research

基　　金：十三五国家重点研发专项(编号:2016YFC1102700);国家自然科学基金(编号:81600910)

摘　　要：目的:研究不同骨挤压手术设计对术后种植体稳定性以及边缘骨吸收的影响,明确骨挤压的手术设计对于术后骨改建的影响。方法:本实验使用不同的手术方法:级差备洞(对照组)、改良骨挤压(实验组A)、常规骨挤压(实验组B)于CD1小鼠愈合拔牙窝内植入相同种植体,并于术后(0、3、21d)处死小鼠,制备组织学染色切片并检测种植体稳定性。结果:实验组B术后3dTRAP染色阳性信号强于实验组A及对照组,并且术后21d种植体颈部观察到明显骨吸收,术后种植体稳定性也明显低于实验组A。结论:通过减小骨挤压后种植窝与种植体的直径差有利于减少术后骨吸收的发生,提高种植修复成功率。Objective:To investigate the effect of different bone condensation methods on the stability of implant and crestal region bone loss,so as to improve the design of condensation protocol.Methods:In this study,three different groups were designed:Undersized Group(Control),Modified Condensation Group(Test A),and Normal Condensation Group(Test B).Different operation protocols were used and the implants with same diameter were inserted into healed maxillary extraction sites of CD1 mice.The mice were killed right after the operation or 3 or 21days after the implant insertion,and the lateral stability testing and histological examinations were performed.Results:Accumulation of TRAP+cell and crestal region bone loss were observed in Test B Group,and the secondary stability of Test B Group was significantly lower than that of Test A Group.Conclusion:Optimizing the condensation protocol is beneficial to reducing occurrence probability of bone resorption after condensation.

关 键 词：骨改建 牙种植体 骨密度 骨挤压 

分 类 号：R783[医药卫生—口腔医学]