高血压脑出血微创钻孔引流术联合高压氧、七叶皂苷钠治疗高血压脑出血效果观察  

Effect of Hypertensive Intracerebral Hemorrhage with Minimally Invasive Drilling and Drainage Combined with Hyperbaric oxygen and Sodium Aescinate in the Treatment of Hypertensive Intracerebral Hemorrhage

作　　者：高峰 张洪源 梁明 GAO Feng;ZHANG Hong-yuan;LIANG Ming(Department of Neurosurgery,Jinan Seventh People’s Hospital,Jiyang,Shandong;Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan,Shandong)

机构地区：[1]济南市第七人民医院神经外科 [2]山东中医药大学第二附属医院

出　　处：《世界最新医学信息文摘》2018年第17期8-9,共2页World Latest Medicine Information Electronic Version

摘　　要：目的回顾性研究高血压脑出血微创钻孔引流术后联合高压氧、或加用七叶皂苷钠治疗高血压脑出血的效果。方法将224例高血压脑出血行微创钻孔引流术的患者按治疗方法分为3组。A组87例术后第7d行高压氧治疗,1次/d,15d为1疗程,共4个疗程;B组61例术后第2d静滴七叶皂苷钠10mg加生理盐水250ml,1次/d,14d为1个疗程,共2个疗程;C组76例联合应用高压氧与七叶皂苷钠,方法同A、B组。观察A、B、C组患者治疗8d和20d后的脑水肿体积;治疗3个月、6个月后行神经功能评分,根据评分评价疗效。结果 A组有效63例,有效率为72.41%;B组有效44例,有效率为72.13%;C组有效64例,有效率为84.21%。C组有效率与A、B组比较,P均<0.05;A、B组比较,P>0.05;治疗后NIHSS评分C组与A、B组比较,P均<0.05;A、B组比较,P>0.05。观察A、B、C组患者治疗8d和20d后的脑水肿体积,C组与A、B组比较,P均<0.05;A、B组比较,P>0.05。结论脑出血微创钻孔引流术联合高压氧与七叶皂苷钠治疗高血压脑出血的效果较好。Objective To retrospectively study the effect of hypertensive intracerebral hemorrhage combined with hyperbaric oxygen or sodium aescinate after minimally invasive drilling and drainage.Methods 224 patients with hypertensive cerebral hemorrhage with minimally invasive drilling and drainage were divided into 3 groups according to the treatment methods.In group A,87 cases of postoperative 7d were treated with hyperbaric oxygen,1 time/d,15d for 1 course,with a total of 4 courses of treatment;In group B,61 cases of postoperative 2d intravenous infusion of sodium aescinate 10mg plus physiological saline 250ml,1 time/d,14d for 1 course,with a total of 2 courses;In group C,76 cases were combined with hyperbaric oxygen and sodium aescinate,and the method is the same as that of the A and B groups.The volume of brain edema after the treatment of 8 d and 20 d was observed in the patients with A,B,and C;After the treatment of 3 months and 6 months,the score of nerve function was evaluated,evaluate the curative effect according to the score.Results In group A,63 cases were effective,and the effective rate was 72.41%;In group B,44 cases were effective,and the effective rate was 72.13%;In group C,64 cases were effective,and the effective rate was 84.21%.The effective rate of group C was compared with that of group A and B,P<0.05;The comparison of group A and B,P>0.05;After treatment,the NIHSS score in group C was compared with that in group A and B,P<0.05;The comparison of group A and B,P>0.05.The volume of brain edema after 8 d and 20 d in the patients with A,B,and C was observed,in group C,compared with group A and B,P<0.05;The comparison of group A and B,P>0.05.Conclusion The minimally invasive drainage of cerebral hemorrhage combined with hyperbaric oxygen and sodium aescinate is better in the treatment of hypertensive intracerebral hemorrhage.

关 键 词：高压氧疗法 七叶皂苷钠 钻孔引流术 高血压脑出血 脑水肿 

分 类 号：R743.34[医药卫生—神经病学与精神病学]