肺癌恶性胸腔积液置管引流患者生活质量调查及影响因素分析  

Investigation of quality of life in lung cancer malignant pleural effusion patients with catheter drainage and analysis of influencing factors

作　　者：苗凯玲 李春燕[1] 侯惠如[1] MIAO Kailing;LI Chunyan;HOU Huiru(Department of Respiratory Medicine,Chinese PLA General Hospital,Beijing 100853,China)

机构地区：[1]解放军总医院呼吸科,北京100853

出　　处：《中国医药导报》2018年第22期64-68,共5页China Medical Herald

基　　金：总后勤部卫生部保健专项科研课题(14BJZ05)

摘　　要：目的调查肺癌恶性胸腔积液置管引流患者的生活质量并探讨影响其生活质量的主要因素。方法选择2017年1~10月解放军总医院呼吸科收治的64例肺癌恶性胸腔积液置管引流患者为观察组,同时选择66例晚期肺癌未出现恶性胸腔积液患者为对照组。采用肺癌生活质量量表(FACT-L 4.0)评估患者生活质量,采用多因素分析对可能影响肺癌恶性胸腔积液置管引流患者生活质量的因素进行分析。结果观察组患者FACT-L量表生理状况、功能状况、肺癌特异模块及生活质量总分低于对照组,差异有统计学意义(P<0.05)。病理分型、体力活动状态(PS)评分、胸腔置管引流次数、文化程度、收入来源、知情状态是肺癌恶性胸腔积液置管引流患者生活质量的影响因素(P<0.05)。PS评分、知情状态、胸腔置管引流次数是肺癌恶性胸腔积液置管引流患者生活质量的独立影响因素(P<0.05)。结论肺癌恶性胸腔积液置管引流患者生活质量差,PS评分、知情状态、胸腔置管引流次数是其独立影响因素。Objective To investigate the quality of life(QOL)of lung cancer malignant pleural effusion patients with catheter drainage and explore the main factors affecting their quality of life.Methods From January to October in 2017,in Department of Respiratory Medicine,Chinese PLA General Hospital,64 cases of lung cancer with malignant pleural effusion were selected as observation group,and at the same time,66 cases of advanced lung cancer without malignant pleural effusion were selected as control group,the quality of life of patients were evaluated by using lung cancer quality of life scale(Fact-l 4.0).Multivariate analysis was used to analyze the factors that may affect the life quality of patients with malignant pleural effusion and drainage of lung cancer.Results The Physical well-being,functional well-being,lung cancer subscale and FACT-L total score in the observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).Pathologic typing,PS score,number of indwelling pleural catheters,education level,source of income,informed status were the factors of quality of life in lung cancer malignant pleural effusion patients with catheter drainage(P<0.05).PS score,informed status,and number of indwelling pleural catheters were independent factors affecting the quality of life of lung cancer malignant pleural effusion patients with catheter drainage(P<0.05).Conclusion The quality of life of lung cancer malignant pleural effusion patients with catheter drainage is poor,PS score,informed state and number of indwelling pleural catheters are independent influencing factors.

关 键 词：肺癌 胸腔积液 引流 生活质量 

分 类 号：R734.2[医药卫生—肿瘤]