2018版ESPCG《益生菌在下消化道症状管理中的应用国际共识》更新解读  

Interpretation of the Probiotics in the Management of Lower Gastrointestinal Symptoms in Clinical Practice:an Evidence-based International Guide Updated in 2018

作　　者：李中信[1] 赵召龙 成士超 LI Zhong-xin;ZHAO Zhao-long;CHENG Shi-chao(No.2 General Surgery Department,Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,China)

机构地区：[1]河北医科大学第四医院外二科,河北省石家庄市050011

出　　处：《中国全科医学》2018年第24期2899-2903,共5页Chinese General Practice

摘　　要：自2013年欧洲初级保健肠胃病学会(ESPCG)首次发布《益生菌在下消化道症状管理中的应用国际共识》,提出某些益生菌可以使肠易激综合征和其他胃肠疾病患者获益以来,近5年又有70多项随机对照试验公布了研究结果。8位专家通过德尔菲法对研究结果进行了系统评价,发布了2018版《益生菌在下消化道症状管理中的应用国际共识》。该共识认为,特定的益生菌可以减轻肠易激综合征患者的胃肠道症状,预防由抗生素和幽门螺杆菌根除治疗引发的腹泻,并显示了良好的安全性。本文就该指南的主要更新要点结合相关文献及数据进行深入分析,旨在帮助全科医生更精准地采用益生菌来治疗或预防下消化道症状。Specified probiotics benefitting irritable bowel syndrome(IBS)and antibiotic-associated diarrhea was put forward by the Probiotics in the Management of Lower Gastrointestinal Symptoms in Clinical Practice:an Evidence-Based International Guide by the ESPCG in 2013,and the effects of probiotics on gastrointestinal diseases were studied and verified further by more than 70 randomized controlled trials in the recent 5 years.Based on a systematic review of the results of these studies combined with a consensus reached by using Delphi technique,8 experts updated the Probiotics in the Management of Lower Gastrointestinal Symptoms:an updated Evidence-Based International Consensus,proposed that specified probiotics can reduce the symptoms of IBS,and can prevent antibiotic-associated diarrhea and diarrhea associated with Helicobacter pylori eradication therapy with good safety.We intensively analyzed the updated main essentials with relevant studies and data,with a view to providing a reference for general practitioners using probiotics to treat or prevent lower gastrointestinal symptoms.

关 键 词：益生菌 下胃肠道 指南 

分 类 号：R57[医药卫生—消化系统]