胸上段食管癌3D-CRT与IMRT的剂量学比较  

Dosimetric Comparison of 3D-CRT and IMRT in Thoracic Esophageal Carcinoma

作　　者：孙光志[1] 王焕[2] SUN Guangzhi;WANG Huan(Radiotherapy Center,Jiangsu Taizhou People's Hospital,Taizhou Jiangsu 225300,China;Tumor Hematology Department,Jiangsu Taizhou People's Hospital,Taizhou Jiangsu 225300,China)

机构地区：[1]江苏省泰州市人民医院放疗中心,江苏泰州225300 [2]江苏省泰州市人民医院肿瘤血液科,江苏泰州225300

出　　处：《中国继续医学教育》2018年第24期58-60,共3页China Continuing Medical Education

摘　　要：目的对胸上段食管癌3D-CRT与IMRT进行剂量学比较。方法选取2016年1月—2018年1月到我院进行治疗的22例胸上段食管癌患者作为研究对象。所有患者均在实际治疗中采用3D-CRT计划。同时,为患者设计IMRT计划进行对比。结果 IMRT与3D-CRT GTV mean(cGy)对比,差异无统计学意义(P>0.05);CTV Dmean、两肺受照射平均剂量(cGy)、V30、V20,心脏V40、V30,脊髓Dmax(cGy)等指标,IMRT均低于3DCRT,差异具有统计学意义(P<0.05)。双肺V10对比,差异无统计学意义(P>0.05);双肺V5对比,IMRT高于3D-CRT,差异具有统计学意义(P<0.05)。结论 IMRT在胸上段食管癌治疗中具有更好的剂量适形性。Objective To compare the dosimetry of 3D-CRT and IMRT in thoracic esophageal carcinoma.Methods 22 patients with upper thoracic esophagus cancer treated in our hospital from January 2016 to January 2018 were selected as the research subjects.All patients were treated with 3D-CRT plan.At the same time,the IMRT plan was designed for the patients to be compared.Results There was no significant difference between IMRT and 3D-CRT GTV mean(cGy)(P>0.05).CTV Dmean,two lung irradiated average dose(cGy),V30,V20,cardiac V40,V30,Dmax(cGy)index of the spinal cord,IMRT were lower than 3DCRT,the difference was statistically significant(P<0.05).There was no significant difference in V10 between two lungs(P>0.05).The contrast between V5 and IMRT was higher than that of 3D-CRT,and the difference was statistically significant(P<0.05).Conclusion IMRT has a better doseconformability in the treatment of thoracic esophageal carcinoma.

关 键 词：胸上段 食管癌 3D-CRT IMRT 剂量 肿瘤靶区 

分 类 号：R734[医药卫生—肿瘤]