脑梗死与颈动脉粥样硬化斑块的相关性研究  

Correlation Between Cerebral Infarction and Carotid Atherosclerotic Plaque

作　　者：晋根芳[1] 葛建国[1] JIN Gen-fang;GE Jiang-guo(Department of neurology,yanling people's hospital,Xuchang,Henan,461200,China)

机构地区：[1]鄢陵县人民医院神经内科,河南许昌461200

出　　处：《临床研究》2018年第8期9-10,共2页Clinical Research

摘　　要：目的探讨颈动脉粥样斑块的性质与脑梗死发生的相关性。方法选择2016年11月~2017年10月在鄢陵县人民医院住院的脑梗死患者264例及同期健康体检者264例(年龄和性别相匹配)进行颈部血管彩色超声检查,比较两组人群颈动脉斑块发生率及不稳定斑块发生率。结果研究组检出颈动脉粥样硬化斑块216例,斑块检出率为81.8%;对照组检出颈动脉粥样硬化斑块22例,斑块检出率8.3%。研究组斑块检出率明显高于对照组,差异有极显著意义(P<0.01)。研究组检出颈动脉不稳定斑块(软斑和混合斑)179例,硬斑37例,不稳定斑块占82.9%;对照组检出颈动脉不稳定斑块(软斑和混合斑)6例,硬斑16例,不稳定斑块占2.3%。研究组颈动脉不稳定斑块检出率明显高于对照组,差异有极显著意义(P<0.01)。结论颈动脉粥样硬化与脑梗死密切相关,导致脑梗死的重要病因是颈动脉粥样硬化斑块的不稳定性。Objective To investigate the relationship between the nature of carotid atherosclerotic plaque and cerebral infarction.Methods 264 patients with cerebral infarction in November 2016 to October 2016 in yanling people's hospital physical examination of and 264 cases(age and gender matched)operated neck vascular color ultrasound examinationthe during the same period,compare the incidence of carotid plaques and incidence of unstable plaques between the two groups.Results 216 cases of carotid atherosclerotic plaque were detected in the study group,and the plaque detection rate was 81.8%.In the control group,22 cases of carotid atherosclerotic plaque were detected,and the plaque detection rate was 8.3%.The plaque detection rate of the study group was significantly higher than that of the control group,and the difference was significant(P<0.01).The study group detected 179 cases of carotid atherosclerotic plaques(soft and mixed plaques),37 cases of hard plaques and 82.9 percent of unstable plaques.The control group detected 6 cases of carotid atherosclerotic plaques(soft and mixed plaques),16 cases of hard plaques and 2.3 percent of unstable plaques.The detection rate of carotid atherosclerotic plaque in the study group was significantly higher than that in the control group(P<0.01).Conclusion Carotid atherosclerosis is closely related to cerebral infarction,and the main cause of cerebral infarction is the instability of carotid atherosclerotic plaque.

关 键 词：颈动脉粥样硬化 脑梗死 彩色多普勒超声 不稳定斑块 

分 类 号：R743.3[医药卫生—神经病学与精神病学]