毒蘑菇中毒素的研究进展  

Review on Toxins from Poisonous Mushroom

作　　者：杨智 胡旭佳[1] YANG Zhi;HU Xu-jia(Faculty of Life Science and Technology,Kunming University of Science and Technology,Kunming,650500,China)

机构地区：[1]昆明理工大学生命科学与技术学院,昆明650500

出　　处：《天然产物研究与开发》2018年第8期1461-1468,共8页Natural Product Research and Development

基　　金：国家自然科学基金(31460430);国家自然科学基金(31660437);国家自然科学基金(31260399)

摘　　要：误食毒蘑菇而中毒一直都威胁着人类的健康,每年国内外都有大量关于蘑菇中毒的报道。毒蘑菇中毒事件引起了越来越多研究者的关注,特别是对毒蘑菇中的毒素成分,中毒机制以及毒素应用等方面。本文根据毒蘑菇中毒的症状,从肝肾中毒,神经中毒,胃肠道中毒和其他中毒四个方面对已知中毒症状的毒蘑菇中所含的毒素以及毒素的活性进行阐述,并对毒蘑菇和毒素的应用进行展望。Poisonous mushrooms have always been a threat to human health,every year there are a large number of reports of mushroom poisoning.Poisonous mushroom has aroused attention of more and more researchers,especially on toxin components in poisonous mushrooms,poisoning mechanism and toxin application.According to the poisoning symptoms of poisonous mushroom,this paper summarized toxins in the known poisoning symptoms of toxic mushrooms and described the activity of these toxins in liver and kidney poisoning,neurotoxicity,gastrointestinal poisoning and other poisoning.Further,the prospects in the application of poisonous mushrooms and toxins were discussed.

关 键 词：毒蘑菇 毒素 中毒症状 活性 

分 类 号：R996.1[医药卫生—毒理学]