读出方向分段采样DWI鉴别舌良恶性病变  

Readout segmentation of long variable echo-trains DWI in differentiating benign and malignant lesions of the tongue

作　　者：文宝红[1] 程敬亮[1] 张会霞[1] 李淑健[1] 王斐斐[1] 张赞霞 薛康康 WEN Baohong;CHENG Jingliang;ZHANG Huixia;LI Shujian;WANG Feifei;ZHANG Zanxia;XUE Kangkang(Department of MRI,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院磁共振科,河南郑州450052

出　　处：《中国医学影像技术》2018年第9期1347-1350,共4页Chinese Journal of Medical Imaging Technology

基　　金：河南省高等学校重点科研项目计划(17A320041)

摘　　要：目的探讨读出方向分段采样(RESOLVE)DWI对舌良恶性病变的鉴别诊断价值。方法回顾性分析经临床及病理证实的120例舌部病变患者的资料,患者术前均接受常规MR检查及RESOLVE DWI。测量病变的ADC值,比较舌良恶性病变间ADC值的差异,应用ROC曲线评价ADC值的诊断舌良恶性病变的价值。结果 120例舌部病变均单发,其中良性病变56例,恶性病变64例。良性病变ADC值为(1.81±0.45)×10^(-3) mm^2/s,恶性病变为(1.02±0.24)×10^(-3) mm^2/s,二者差异有统计学意义(t'=12.21,P<0.001)。以ADC值诊断舌部良恶性病变的ROC曲线AUC为0.976(P<0.001),以ADC值=1.25×10^(-3) mm^2/s为临界值,诊断舌良恶性病变的敏感度为94.64%(53/56),特异度为93.75%(60/64)。结论 RESOLVE DWI鉴别诊断舌良恶性病变具有一定参考价值。Objective To investigate the diagnostic value of readout segmentation of long variable echo-trains(RESOLVE)DWI in evaluation of benign and malignant lesions of the tongue.Methods Totally 120 patients with lingual lesions confirmed by clinical information and pathology were retrospectively analyzed.All patients underwent preoperative routine MRI and RESOLVE DWI,and the ADC value was calculated.ADC values were compared between benign and malignant lesions of the tongue.Diagnostic performance of ADC value was evaluated with ROC curve.Results All the lesions were solitary,including 56 benign lesions and 64 malignant ones.The mean ADC value of benign lesions and malignant tumor was(1.81±0.45)×10-3 mm 2/s and(1.02±0.24)×10-3 mm 2/s,respectively.There was statistical difference between benign and malignant lesions(t'=12.21,P<0.001).The AUC of the ROC of ADC value differentiating benign and malignant lesions of the tongue was 0.976(P<0.001).Taking ADC=1.25×10-3 mm 2/s as the threshold for diagnosing benign and malignant lesions of the tongue,the sensitivity was 94.64%(53/56)and specificity was 93.75%(60/64).Conclusion RESOLVE DWI can be applied in differential diagnosis of benign and malignant lesions of the tongue.

关 键 词：舌肿瘤 磁共振成像 表观扩散系数 读出方向分段采样 

分 类 号：R739.86[医药卫生—肿瘤] R445.2[医药卫生—临床医学]